Violacein/beta-cyclodextrin inclusion complex formation studied by measurements of diffusion coefficient and circular dichroism

dc.creatorDe Azevedo, MBM
dc.creatorAlderete, JB
dc.creatorLino, ACS
dc.creatorLoh, W
dc.creatorFaljoni-Alario, A
dc.creatorDuran, N
dc.date2000
dc.dateMAY
dc.date2014-12-02T16:30:52Z
dc.date2015-11-26T17:40:49Z
dc.date2014-12-02T16:30:52Z
dc.date2015-11-26T17:40:49Z
dc.date.accessioned2018-03-29T00:22:32Z
dc.date.available2018-03-29T00:22:32Z
dc.identifierJournal Of Inclusion Phenomena And Macrocyclic Chemistry. Springer, v. 37, n. 41730, n. 67, n. 74, 2000.
dc.identifier0923-0750
dc.identifierWOS:000086963700004
dc.identifier10.1023/A:1008186706573
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/72783
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/72783
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/72783
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1286835
dc.descriptionThe formation of inclusion compounds between violacein and beta-cyclodextrin was studied by diffusion and circular dichroism measurements. The present work was undertaken to explore the feasibility of the beta-cyclodextrin in reducing the toxicity and enhancing the antitumoral efficacy of violacein by forming an inclusion complex. The results of the two experiments are in good agreement, suggesting the formation of 1 : 1 and 1 : 2 complexes. The diffusion coefficient measurements enabled estimates of the sizes of the complexes involved. From the circular dichroism and computational calculations it was possible to view a preference for inclusion of the most polar part of the molecule to form a 1 : 2 inclusion complex. We expect that this work proves the potential of these techniques to determining complex stoichiometry.
dc.description37
dc.description41730
dc.description67
dc.description74
dc.languageen
dc.publisherSpringer
dc.publisherDordrecht
dc.publisherHolanda
dc.relationJournal Of Inclusion Phenomena And Macrocyclic Chemistry
dc.relationJ. Incl. Phenom. Macrocycl. Chem.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectbeta-cyclodextrin
dc.subjectinclusion complex
dc.subjectstoichiometry
dc.subjectviolacein
dc.subjectinduced circular dichroism
dc.subjectChromobacterium-violaceum
dc.subjectAqueous-solution
dc.subjectBeta-cyclodextrin
dc.subjectChemistry
dc.subjectBehavior
dc.subjectRotaxane
dc.subjectPigment
dc.subjectPhenols
dc.subjectAcid
dc.titleViolacein/beta-cyclodextrin inclusion complex formation studied by measurements of diffusion coefficient and circular dichroism
dc.typeArtículos de revistas


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