Artículos de revistas
Progestin-only contraception prevents bone loss in postpartum breastfeeding women
Registro en:
Contraception. Elsevier Science Inc, v. 85, n. 4, n. 374, n. 380, 2012.
0010-7824
WOS:000301999100009
10.1016/j.contraception.2011.08.015
Autor
Costa, ML
Cecatti, JG
Krupa, FG
Rehder, PM
Sousa, MH
Costa-Paiva, L
Institución
Resumen
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Background: There are an increase in bone loss during the first 6 months postpartum and a complete recovery postweaning. A few studies of steroid contraceptive use during this period provide some evidence towards protection of bone loss with progestin-only contraceptive methods. Objective: The study was conducted to evaluate forearm bone mineral density (BMD) of breastfeeding postpartum women using nonhormonal and progestin-only contraceptive methods. Study Design: A prospective cohort study of postpartum women had an analysis performed at 6 months postpartum correlating BMD with contraceptive use. Forearm BMD was measured 7-10 days, 3 months and 6 months postpartum. Eighty-two women were analyzed, comparing nonhormonal (54) and progestin-only (28) contraceptive methods. Information about breastfeeding duration, amenorrhea and body mass index was collected. Results: Baseline characteristics of the study population showed no statistical differences between the groups. The median duration of breastfeeding for both groups was 183 days. A significant BMD decrease was observed for the nonhormonal group (p<.001); however, no statistical difference was detected for the progestin-only group. Body mass index, BMD at 7-10 days postpartum and total duration of breastfeeding were positively correlated with BMD at 6 months. Conclusions: Our findings suggest a preventive effect towards postpartum bone loss with progestin-only contraception in breastfeeding women. (C) 2012 Elsevier Inc. All rights reserved. 85 4 374 380 Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) FAEPEX/UNICAMP [421/2010] Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) FAPESP [2006/04555-3] FAEPEX/UNICAMP [421/2010]