Artículos de revistas
Total synthesis of (+)-crocacin D
Registro en:
Journal Of Organic Chemistry. Amer Chemical Soc, v. 70, n. 6, n. 2225, n. 2234, 2005.
0022-3263
WOS:000227566400036
10.1021/jo047732k
Autor
Dias, LC
de Oliveira, LG
Vilcachagua, JD
Nigsch, F
Institución
Resumen
The total synthesis of (+)-crocacin D is described. The convergent asymmetric synthesis relies on the use of a Stille cross-coupling between an (E)-vinyl stannane with an (E)-vinyl iodide to establish the (E,E)-dienamide moiety followed by a mild and efficient copper-catalyzed coupling between (+)-crocacin C and a (Z)-vinyl iodide to establish the challenging (Z)-enamide function. 70 6 2225 2234