The aim of the present work is to apply the topological sensitivity analysis (TSA) to large-deformation elasticity based on the total Lagrangian formulation. The TSA results in a scalar function, denominated topological derivative, that gives for each point of the domain the sensitivity of a given cost function when a small hole is created. An approximated expression for the topological derivative is obtained by numerical asymptotic analysis. Numerical results of the presented approach are considered for elastic plane problems.372149163