| dc.creator | Costa, M | |
| dc.creator | Perles, EC | |
| dc.creator | Fujiwara, FY | |
| dc.creator | Imamura, PM | |
| dc.date | 2000 | |
| dc.date | APR | |
| dc.date | 2014-12-02T16:24:55Z | |
| dc.date | 2015-11-26T17:20:12Z | |
| dc.date | 2014-12-02T16:24:55Z | |
| dc.date | 2015-11-26T17:20:12Z | |
| dc.date.accessioned | 2018-03-29T00:07:49Z | |
| dc.date.available | 2018-03-29T00:07:49Z | |
| dc.identifier | Phytochemistry. Pergamon-elsevier Science Ltd, v. 53, n. 8, n. 851, n. 854, 2000. | |
| dc.identifier | 0031-9422 | |
| dc.identifier | WOS:000086975500007 | |
| dc.identifier | 10.1016/S0031-9422(99)00583-X | |
| dc.identifier | http://www.repositorio.unicamp.br/jspui/handle/REPOSIP/79245 | |
| dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/79245 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/79245 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1283078 | |
| dc.description | Reduction of the alpha,beta-unsaturated ester moiety of (+)-methyl hardwickiate with magnesium in methanol afforded methyl (4aS,6S,8aS, 1R,5R)-5,6,8a-trimethyl-5-[2'-(3 '-oxoyl)-ethyl-perhydro-1-naphthalenyl]-carboxaylate, while reduction with sodium in n-propanol, followed by esterification with diazomethane, furnished its C-4 epimer. After comparison of thr H-1- and C-13-NMR data of these compounds with those reported for crolechinic acid isolated from Croton lechleri, a stereochemical revision for the natural product is suggested. (C) 2000 Elsevier Science Ltd. All rights reserved. | |
| dc.description | 53 | |
| dc.description | 8 | |
| dc.description | 851 | |
| dc.description | 854 | |
| dc.language | en | |
| dc.publisher | Pergamon-elsevier Science Ltd | |
| dc.publisher | Oxford | |
| dc.publisher | Inglaterra | |
| dc.relation | Phytochemistry | |
| dc.relation | Phytochemistry | |
| dc.rights | fechado | |
| dc.rights | http://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy | |
| dc.source | Web of Science | |
| dc.subject | reduction | |
| dc.subject | (+)-methyl hardwickiate | |
| dc.subject | stereochemistry | |
| dc.subject | crolechinic acid | |
| dc.subject | Alpha,beta-unsaturated Esters | |
| dc.subject | Selective Reduction | |
| dc.subject | Croton-lechleri | |
| dc.subject | Dragons Blood | |
| dc.subject | South-america | |
| dc.subject | Magnesium | |
| dc.subject | Methanol | |
| dc.title | Synthesis of methyl dihydrohardwickiate and its C-4 epimer. Structural amendment of natural crolechinic acid | |
| dc.type | Artículos de revistas | |
