Artículos de revistas
Enantioselective approach to the asymmetric synthesis of (6R)-hydroxymethyl-5,6-dihydro-2H-pyran-2-one. A formal synthesis of (R)-argentilactone and total synthesis of (R)-goniothalamin
Registro en:
Arkivoc. Arkat Usa Inc, n. 118, n. 126, 2003.
1551-7012
WOS:000220556500013
Autor
de Fatima, A
Pilli, RA
Institución
Resumen
The asymmetric synthesis of the (6R)-hydroxymethyl-5,6-dihydro-2H-pyran-2-one, a key intermediate in the formal synthesis of (R)-argentilactone, and the total synthesis of ( R)goniothalamin are described. Our aproach involved the Lemieux-Johnson oxidative cleavage, enantioselective Keck allylation, ring-closing metathesis and Wittig olefination. 10 118 126