Artículos de revistas
Hydrolytic degradation of poly(para-dioxanone) films prepared by casting or phase separation
Registro en:
Polymer Degradation And Stability. Elsevier Sci Ltd, v. 78, n. 3, n. 405, n. 411, 2002.
0141-3910
WOS:000179151600001
10.1016/S0141-3910(02)00174-X
Autor
Pezzin, APT
Duek, EAR
Institución
Resumen
Poly(para-dioxanone) (PPD) films have been prepared by casting and phase separation, varying the concentration of the polymeric solution (2.5, 5 and 10% w/v) using hexafluoro-isopropanol as solvent and ethanol as non-solvent. The hydrolytic degradation of PPD films was studied. The samples were immersed in a phosphate buffer solution (pH = 7.4) at 37 +/- 1 degreesC for 1, 2, 4 and 6 weeks. The degradation was evaluated by analyzing the variation of melting enthalpy (DeltaH(m)) and crystallinity, determined by differential scanning calorimetry (DSC), initial temperature of mass loss (T-onset) and temperature of maximum mass loss (T-peak), determined by thermogravimetric analysis (TGA), and morphological changes observed by scanning electron microscopy (SEM). (C) 2002 Elsevier Science Ltd. All rights reserved. 78 3 405 411