Artículos de revistas
Effect of additives on the bioreduction of 2-chloro-1-phenyl-2-propen-1-one by baker's yeast
Registro en:
Journal Of Molecular Catalysis B-enzymatic. Elsevier Science Bv, v. 15, n. 41699, n. 23, n. 28, 2001.
1381-1177
WOS:000171065600004
10.1016/S1381-1177(00)00249-6
Autor
Filho, EPS
Rodrigues, JAR
Moran, PJS
Institución
Resumen
The reduction of 2-chloro-1-phenyl-2-propen-1-one (2) by baker's yeast (Saccharomyces cerevisiae) was performed under various reaction conditions, such as the addition of allyl alcohol, sucrose, thermal pre-treatment of the cells and use of a citrate buffer at pH 4.0. 2-Chloro-1-phenyl-1-propan-1-one (3) was produced after 2 h in a poor enantiomeric excess (ee) while after a longer period of fermentation, the compounds IR,2R- and IR,2S-2-chloro-1-phenylpropan-1-ol (4) were obtained at 80-90 and 28-63% ee. (C) 2001 Elsevier Science B.V. All rights reserved. 15 41699 23 28