Artículos de revistas
Malignant mixed Mullerian tumor of the uterine cervix with neuroendocrine differentiation
Registro en:
International Journal Of Gynecological Cancer. Blackwell Publishing Inc, v. 12, n. 2, n. 223, n. 227, 2002.
1048-891X
WOS:000175252400016
10.1046/j.1525-1438.2002.01100.x
Autor
Ribeiro-Silva, A
Novello-Vilar, A
Cunha-Mercante, AM
Andrade, LALD
Institución
Resumen
Malignant mixed Mullerian tumors (MMMTs) are rare neoplasms. We report the clinical, pathologic, and immunohistochemical features of an MMMT primary of uterine cervix. This lesion was composed of a poorly differentiated epithelial component (cytokeratin positive) and a spindle cell component (vimentin positive) with heterologous (myoblastic) differentiation (focal 1A4 positive). There were also cells with neuroendocrine features that expressed S-100 and chromogranin A. Along with a brief review of this amazing neoplasm, some histogenetic concepts relevant to this case are discussed. To our knowledge this is the first report of a malignant mixed Mullerian tumor of the uterine cervix with neuroendocrine differentiation. 12 2 223 227