Artículos de revistas
Synthesis of (5R)-4-Methyl-5-phenyl-1,3,4-oxadiazinan-2-one and some N-acyl derivatives from (R)-phenylglycine
Registro en:
Synthesis-stuttgart. Georg Thieme Verlag Kg, n. 15, n. 2578, n. 2582, 2005.
0039-7881
WOS:000232503200018
10.1055/s-2005-872101
Autor
Rodrigues, A
Olivato, PR
Rittner, R
Institución
Resumen
(5R)-4-Methyl-5 -pheny 1- 1,3,4-oxadiazinan-2-one was synthesized from (R)-phenylelycine in five steps and in 65% overall yield. In addition, a convenient and practical method for N-acylation of 1,3,4-oxadiazinan-2-one directly with acids in the presence of DCC and catalytic quantities of DMAP is described. The acylated products were obtained in excellent yields. 15 2578 2582