The effects of 780-nm low-level laser therapy on muscle healing process after cryolesion

dc.creatorBrunelli, RM
dc.creatorRodrigues, NC
dc.creatorRibeiro, DA
dc.creatorFernandes, K
dc.creatorMagri, A
dc.creatorAssis, L
dc.creatorParizotto, NA
dc.creatorCliquet, A
dc.creatorRenno, ACM
dc.creatorAbreu, DCC
dc.date2014
dc.dateJAN
dc.date2014-07-30T19:43:55Z
dc.date2015-11-26T16:56:27Z
dc.date2014-07-30T19:43:55Z
dc.date2015-11-26T16:56:27Z
dc.date.accessioned2018-03-28T23:43:51Z
dc.date.available2018-03-28T23:43:51Z
dc.identifierLasers In Medical Science. Springer London Ltd, v. 29, n. 1, n. 91, n. 96, 2014.
dc.identifier0268-8921
dc.identifier1435-604X
dc.identifierWOS:000329834200012
dc.identifier10.1007/s10103-013-1277-6
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/73787
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/73787
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1277376
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionThe objective of this study was to assess the effects of 780-nm low-level laser therapy at different periods of 7, 14 and 21 days after cryolesion, including the dose (10 or 50 J/cm(2)), to promote a better muscle repair evidenced by histopathological and immunohistochemical analyses. Fifty-four male rats were divided into three groups: injured control group (CG)-injured animals without any treatment; injured 780-nm laser-treated group, at 10 J/cm(2) (G10); and injured 780-nm laser-treated group, at 50 J/cm(2) (G50). Each group was divided into three subgroups (n = 6): 7, 14 and 21 days post-injury. Histopathological findings revealed better organised muscle fibres in the G10 and G50 during the periods of 7 and 14 days compared to the CG. The G10 and G50 during the 7 days showed a significant reduction (p < 0.05) of lesion area compared to the CG, without differences between groups treated for 14 and 21 days. The G10 showed an increase of the amount of vessels after 14 days compared to the G50, but not in relation to controls. With regard to the immunohistochemical analyses of the MyoD factor, the G10 and G50 during the 7 days showed higher concentrations of immunomarkers than controls. Myogenin immunomarkers were similarly observed at days 7 and 14 in all the three groups analysed, whereas immunomarkers were found in none of the groups after 21 days of laser therapy. The results showed that laser, regardless the applied dose, has positive effects on muscle repair.
dc.description29
dc.description1
dc.description91
dc.description96
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.descriptionCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.languageen
dc.publisherSpringer London Ltd
dc.publisherLondon
dc.publisherInglaterra
dc.relationLasers In Medical Science
dc.relationLasers Med. Sci.
dc.rightsfechado
dc.rightshttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dc.sourceWeb of Science
dc.subjectPhysical resource
dc.subjectQualitative histological analysis
dc.subjectVessel counting
dc.subjectLesion area
dc.subjectMyoD
dc.subjectMyogenin
dc.subjectSkeletal-muscle
dc.subjectRegeneration
dc.subjectIrradiation
dc.subjectInjury
dc.subjectRepair
dc.subjectRats
dc.titleThe effects of 780-nm low-level laser therapy on muscle healing process after cryolesion
dc.typeArtículos de revistas


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