Artículos de revistas
In Vitro Degradation of Poly (L-co-D, L lactic acid) Containing PCL-T
Registro en:
Polimeros-ciencia E Tecnologia. Assoc Brasil Polimeros, v. 24, n. 1, n. 1, n. 8, 2014.
0104-1428
WOS:000334404600001
10.4322/polimeros.2014.056
Autor
Duarte, MAT
Duek, EAD
Motta, AC
Institución
Resumen
The application of polymer-based bioresorbable temporary devices in the medical field grows continuously, and professionals from several areas act to solve problems related to body functions lost due to diseases, accidents or natural wear. Here we study the influence from poly(caprolactonetriol) (PCL-T) on the degeneration process in the copolymer poly(L-co-DL-lactic acid) (PLDLA) membrane, by producing PLDLA/PCL-T blends with 90/10, 70/30 and 50/50 relative concentrations. The data for in vitro degradation showed that PCL-T decreases the rate of PLDLA. This was obtained with the following techniques: Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Gel Permeation Chromatography (GPC) and Scanning Electron Microscopy (SEM). Therefore, it is possible to vary the membrane degradation rate by changing the blend composition, which is a tool to tailor a biomaterial. 24 1 1 8