In this payer, a 1D hydrodynamic model has been developed for gas hold-up and liquid circulation velocity prediction in air-lift reactors. The model is based on momentum balance equations and has been adjusted to experimental data collected on a pilot plant reactor equipped with two types of gas distributors and using water and water/butanol as the liquid phase. Different techniques of signal analysis have also been applied to pressure fluctuations in order to extract information about flow regimes and regime transitions. A good knowledge of the now pattern is essential to establish adequate correlations for the hydrodynamic model.1741824607615