Artículos de revistas
Perspective: Indigenous sugarcane yeast strains as ideal biological platforms for the delivery of next generation biorefining technologies
Registro en:
International Sugar Journal. Int Sugar Journal Ltd, v. 112, n. 1334, n. 86, n. 89, 2010.
0020-8841
WOS:000279444400022
Autor
Argueso, JL
Pereira, GAG
Institución
Resumen
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) In the industrial process used to convert sugarcane juice to bioethanol, the yeast cells responsible for the fermentation are often exposed to severe biotic and abiotic stresses. These include the constant entry of microbial contaminants into the system, prolonged cell recycling, ethanol toxicity, and osmotic, oxidative, and temperature stresses. In the past decade, several indigenous yeast strains have been isolated in Brazil that combine excellent adaptation to this hostile environment and high performance in bioethanol fermentation. Recent genetic studies have demonstrated that these strains have heterogeneous genome architectures, and established a strong link between this genomic complexity and their adaptation to the industrial environment. We propose a role for these highly adapted organisms as biological platforms for the delivery of a wide range of future biorefining technologies. By adopting genetic manipulation strategies that do not interfere with their genomic complexity, it should be possible create new yeast strains that are much more likely to succeed in large scale industrial applications. 112 1334 86 89 Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) ETH Bioenergia Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) FAPESP [PITE3 - 07/58336-3]