The challenge of early systemic sclerosis for the EULAR Scleroderma Trial and Research group (EUSTAR) community. It is time to cut the Gordian knot and develop a prevention or rescue strategy

dc.creatorMatucci-Cerinic, M
dc.creatorAllanore, Y
dc.creatorCzirjak, L
dc.creatorTyndall, A
dc.creatorMuller-Ladner, U
dc.creatorDenton, C
dc.creatorValentini, G
dc.creatorDistler, O
dc.creatorFligelstone, K
dc.creatorTyrrel-Kennedy, A
dc.creatorFarge, D
dc.creatorKowal-Bielecka, O
dc.creatorvan den Hoogen, F
dc.creatorCutolo, M
dc.creatorSampaio-Barros, PD
dc.creatorNash, P
dc.creatorTakehara, K
dc.creatorFurst, DE
dc.date2009
dc.dateSEP
dc.date2014-11-15T04:09:39Z
dc.date2015-11-26T16:30:50Z
dc.date2014-11-15T04:09:39Z
dc.date2015-11-26T16:30:50Z
dc.date.accessioned2018-03-28T23:11:54Z
dc.date.available2018-03-28T23:11:54Z
dc.identifierAnnals Of The Rheumatic Diseases. B M J Publishing Group, v. 68, n. 9, n. 1377, n. 1380, 2009.
dc.identifier0003-4967
dc.identifierWOS:000268888600001
dc.identifier10.1136/ard.2008.106302
dc.identifierhttp://www.repositorio.unicamp.br/jspui/handle/REPOSIP/78118
dc.identifierhttp://www.repositorio.unicamp.br/handle/REPOSIP/78118
dc.identifierhttp://repositorio.unicamp.br/jspui/handle/REPOSIP/78118
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/1270060
dc.descriptionEarly diagnosis of systemic sclerosis (SSc) may allow the start of treatment that could slow disease progression. For this reason early diagnosis of the disease is of pivotal importance. However, the lack of diagnostic criteria and valid predictors significantly limit patient evaluation and the use of potentially effective drugs in the earliest phase of SSc. Early SSc may be suspected on the basis of Raynaud's phenomenon, puffy fingers, autoantibodies and SSc capillaroscopic pattern. In practice, the aim is to have criteria for the diagnosis of very early SSc. The criteria that are proposed are obviously provisional and need to be validated: (a) initially through a Delphi technique; (b) thereafter perhaps using already available datasets; but (c) of critical importance, through prospective studies. Only after prospective studies can these potential criteria be considered validated. The consensus on criteria for the classification of very early SSc might be part of the evolving EULAR/ACR project of reclassification of SSc.
dc.description68
dc.description9
dc.description1377
dc.description1380
dc.descriptionEULAR
dc.descriptionActelion
dc.descriptionEncysive
dc.descriptionPfizer
dc.languageen
dc.publisherB M J Publishing Group
dc.publisherLondon
dc.publisherInglaterra
dc.relationAnnals Of The Rheumatic Diseases
dc.relationAnn. Rheum. Dis.
dc.rightsfechado
dc.sourceWeb of Science
dc.subjectConnective-tissue Disease
dc.subjectSecondary Raynauds-phenomenon
dc.subjectClassification Criteria
dc.subjectNailfold Capillaroscopy
dc.subjectFollow-up
dc.subjectSensitivity
dc.subjectTransition
dc.titleThe challenge of early systemic sclerosis for the EULAR Scleroderma Trial and Research group (EUSTAR) community. It is time to cut the Gordian knot and develop a prevention or rescue strategy
dc.typeArtículos de revistas


Este ítem pertenece a la siguiente institución