Artículos de revistas
Addition of allyltrichlorostannanes to aldehydes: application in the synthesis of 4-N-Boc-amino-3-hydroxy ketones
Registro en:
Tetrahedron Letters. Pergamon-elsevier Science Ltd, v. 49, n. 3, n. 557, n. 561, 2008.
0040-4039
WOS:000253061900035
10.1016/j.tetlet.2007.11.072
Autor
Dias, LC
Fattori, J
Perez, CC
Institución
Resumen
We wish to describe here the diastereoselective reaction between chiral N-Boc-alpha-amino aldehydes and achiral allyltrichlorostannanes leading to 1,2-syn-N-Boc-alpha-amino alcohols, which are treated with catalytic amounts of OSO4 in the presence of NaIO4 to provide the corresponding 4-N-Boc-amino-3-hydroxy ketones. (C) 2007 Elsevier Ltd. All rights reserved. 49 3 557 561