Artículos de revistas
Enantioselective syntheses of (R)- and (S)-argentilactone and their cytotoxic activities against cancer cell lines
Registro en:
Bioorganic & Medicinal Chemistry. Pergamon-elsevier Science Ltd, v. 12, n. 20, n. 5437, n. 5442, 2004.
0968-0896
WOS:000224446800017
10.1016/j.bmc.2004.07.044
Autor
de Fatima, A
Kohn, LK
Antonio, MA
de Carvalho, JE
Pilli, RA
Institución
Resumen
Concise total syntheses of (R)- and (S)-argentilactone have been developed via enantioselective catalytic allylation (ECA) and ring-closing metathesis pathways (four steps, 39% overall yield and 82-84% ee) from 2-octynal and their in vitro activity against cancer cells is described. (C) 2004 Elsevier Ltd. All rights reserved. 12 20 5437 5442