The advent of highly active antiretroviral therapy has promoted a reduction in mortality due to HIV. Thus more women are living longer after receiving a diagnosis of HIV infection. With an increase in survival, topics related to the menopausal transition in HIV-infected women have emerged, such as age at menopause, bone mineral density and menopause-related symptoms. To this end, several studies have investigated age at menopause (AM) in HIV-infected women. The present paper reviews these studies and discusses the possible clinical implications of determining AM for HIV-positive women.2428486