Artículos de revistas
Short Stature In Chronic Kidney Disease: Physiopathology And Treatment With Growth Hormone [baixa Estatura Na Doença Renal Crônica: Fisiopatologia E Tratamento Com Hormônio De Crescimento]
Registro en:
Arquivos Brasileiros De Endocrinologia E Metabologia. , v. 52, n. 5, p. 783 - 791, 2008.
42730
2-s2.0-51949094002
Autor
De Oliveira J.C.
Siviero-Miachon A.A.
Spinola-Castro A.M.
Belangero V.M.S.
Guerra Jr. G.
Institución
Resumen
Growth failure is frequent and a clinically important issue in children with chronic kidney disease (CKD). Many factors contribute to impaired growth in these children, including abnormalities in the growth hormone (GH) - insulin-like growth factor 1 (IGF-1) axis, malnutrition, acidosis, renal bone disease and glucocorticoid associated treatment. The management of growth failure in children with CKD is complicated by the presence of other-disease related complications requiring medical intervention. Despite evidence of GH efficacy and safety in this population, this therapy is still underutilized. 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