Artículos de revistas
Desorption/ionization Efficiencies Of Triacylglycerols And Phospholipids Via Easi-ms
Registro en:
Journal Of Mass Spectrometry. John Wiley And Sons Ltd, v. 49, n. 5, p. 335 - 341, 2014.
10765174
10.1002/jms.3366
2-s2.0-84900037361
Autor
Fernandes A.M.A.P.
Fernandes G.D.
Barrera-Arellano D.
De Sa G.F.
Lins R.D.
Eberlin M.N.
Alberici R.M.
Institución
Resumen
Knowledge of the major effects governing desorption/ionization efficiency is required for the development and application of ambient mass spectrometry. Although all triacylglycerols (TAG) have the same favorable protonation and cationization sites, their desorption/ionization efficiencies can vary dramatically during easy ambient sonic-spray ionization because of structural differences in the carbon chain. To quantify this somewhat surprising and drastic effect, we have performed a systematic investigation of desorption/ionization efficiencies as a function of unsaturation and length for TAG as well as for diacylglycerols, monoacylglycerols and several phospholipids (PL). Affinities for Na+ as a function of unsaturation level have also been assayed via comprehensive metadynamics calculations to understand the influence of this phenomenon on the ionization efficiency. 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