Artículos de revistas
Plasmatic Lipid Profile Indicators Related To Insulin Resistance [indicadores Do Perfil Lipídico Plasmático Relacionados à Resistência à Insulina]
Registro en:
Revista Da Associacao Medica Brasileira. , v. 55, n. 3, p. 342 - 346, 2009.
1044230
2-s2.0-69149101311
Autor
Vasques A.C.J.
Rosado L.E.F.P.L.
Rosado G.P.
Ribeiro R.C.L.
Franceschini S.C.C.
Priore S.E.
Geloneze B.
de Oliveira D.R.
Institución
Resumen
Purpose: To investigate the effectiveness of biochemical indicators from the plasmatic lipid profile to identify the insulin resistance (IR), assessed by the HOMA-IR index (Homeostasis Model Assessment - Insulin Resistance). Methods: 138 healthy men (20-59 years) were evaluated. The lipid profile biochemical indicators analyzed were the following: triglycerides (TG), total cholesterol (TC), HDL-C, LDL-C, and TC/HDL-C and TG/HDL-C ratios. The percentile 75 was considered as the cut-off point for IR. Statistical analysis consisted of Spearman correlation coefficient, ROC curves and calculation of the areas under the curve (AUC). result. The TG/HDL-C ratio showed the strongest correlation and the greatest AUC (r = 0.334 and AUC = 0.724 ± 0.046, p < 0.001) respectively, followed by the HDL-C (r = -0.313 and AUC = 0.716 ± 0.052, p < 0.01), the TG (r = 0.261 and AUC = 0.048 ± 0.674, p < 0.01) and CT/HDL-C ratio (r = 0.259 and AUC = 0.655 ± 0.05, p < 0.01). Results for TC and LDL-C showed no statistical significant (p > 0.05). Conclusion. 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