[No abstract available]506 A 607610Pessin, J.E., Saltiel, A.R., Signaling pathways in insulin action: Molecular targets of insulin resistance (2000) J Clin Invest, 106, pp. 165-169Myers, M.G., White, M.F., Insulin signal transduction and the IRS proteins (1996) Annu Rev Pharmacol Toxicol, 36, pp. 615-658Margolis, R.U., Altszuler, N., Insulin in the cerebrospinal fluid (1967) Nature, 215, pp. 1375-1376Wallum, B., Taborsky G.J., Jr., Porte D., Jr., Fliguewicz, D.P., Jacobson, L., Beard, J.C., Ward, W.K., Dorsa, D., Cerebrospinal fluid insulin levels increase during intravenous insulin infusions in man (1987) J Clin Endocrinol Metab, 64, pp. 190-194Fernandes, M.L.L.A., Saad, M.J.A., Velloso, L.A., Insulin induces tyrosine phosphorylation of the insulin receptor and Shc, and Shc/Grb2 association in cerebellum but not in forebrain cortex of rats (1999) Brain Res, 826, pp. 74-82Carter, D.A., Wobken, J.D., Dixit, P.K., Bauer, G.A., Immunoreactive insulin in rat salivary glands and its dependence on age and serum insulin levels (1995) Proc Soc Exp Biol Med, 209, pp. 245-250Westrom, B.R., Ekman, R., Svendsen, L., Svendsen, J., Karlsson, B.W., Levels of immunoreactive insulin, neurotensin and bombesin in porcine colostrum and milk (1987) J Pediatr Gastroenterol Nutr, 6, pp. 460-465Saragas, S., Arffa, R., Rabin, B., Kronish, J., Miller, D., Mayman, C., Reversal of wound strength retardation by addition of insulin to corticosteroid therapy (1985) Ann Ophthalmol, 17, pp. 428-430Woost, P.G., Brightwell, J., Eiferman, R.A., Schultz, G.S., Effect of growth factors with dexamethasone on healing of rabbit corneal stromal incisions (1985) Exp Eye Res, 40, pp. 47-60Pillion, D.J., Bartlett, J.D., Meezan, E., Yanf, M., Crain, J., Grizzle, W.E., Systemic absorption of insulin delivered topically to the rat eye (1991) Invest Ophthalmol Vis Sci, 32, pp. 3021-3027Sullivan, D.A., Hann, L.E., Hormonal influence on the secretory immune system of the eye (1989) J Steroid Biochem, 34, pp. 253-262Sullivan, D.A., Wickham, L.A., Rocha, E.M., Kelleher, R.S., Silveira, L.A., Toda, I., Influence of gender, sex steroids hormones and the hypothalamic-pituitary axis on the structure and function of the lacrimal gland (1998) Adv Exp Med Biol, 438, pp. 11-42Woost, P.G., Jumblatt, M.M., Eiferman, R.A., Schultz, G.S., Growth factors and corneal endothelial cells: I. Stimulation of bovine corneal endothelia cell DNA synthesis by defined growth factors (1992) Cornea, 11, pp. 1-10Lindberg, K., Brown, M.E., Chaves, H.V., Kenyon, K.R., Rheinwald, J.G., In vitro propagation of human ocular surface cells for transplantation (1993) Invest Ophthalmol Vis Sci, 34, pp. 2672-2679Pellegrini, G., Traverso, C.E., Franzi, A.T., Zingirian, M.Z., Canceda, R., De Luca, M., Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium (1997) Lancet, 349, pp. 990-993Rocha, E.M., Wickham, L.A., Silveira, L.A., Krenzer, K.L., Toda, I., Sullivan, D.A., Identification of androgen receptor protein and 5μ-reductase mRNA in human ocular tissues (2000) Br J Ophthalmol, 84, pp. 76-84Rocha, E.M., Cunha, D.A., Carneiro, E.M., Boschero, A.C., Saad, M.J.A., Velloso, L.A., (2000) Identification of Insulin in the Tear Film and Insulin Receptor and Insulin-like Growth Factor-I Receptor on the Human Ocular Surface, , Submitted for publication