Artículos de revistas
Use Of Autologous Fibrin Glue In Dermatologic Surgery: Application Of Skin Graft And Second Intention Healing.
Registro en:
São Paulo Medical Journal = Revista Paulista De Medicina. , v. 116, n. 4, p. 1747 - 1752, 1998.
15163180
2-s2.0-0032106871
Autor
de Moraes A.M.
Annichino-Bizzacchi J.M.
Rossi A.B.
Institución
Resumen
OBJECTIVE: To evaluate the efficiency of biological sealant, an autologous fibrin glue, in dermatological surgery. DESIGN: Randomized clinical trial. SETTING: The Dermatology Service of Hospital das Clinicas, Universidade de Campinas (UNICAMP), referral center. PATIENTS: 14 patients with malign epithelial cutaneous tumors participated in the evaluation, each having two tumors, generally facial and symmetrical, in order to perform a comparative evaluation on the same individual. PROCEDURES: The glue was prepared beforehand with a sample of autologous blood. Surgical extirpation of the tumor was followed by grafts or second intention healing. OUTCOMES: The efficiency of the sealant was then evaluated in relation to hemostasis, adhesion, surgical time and evolution of the granulation tissue, clinically and histologically. RESULTS: Immediate hemostasis and graft adhesion, with a significant reduction of surgical time, and in the open wounds there was immediate hemostasis and a clinical increase in granulation tissue, but with no histological differences among the groups on the 7th day. CONCLUSION: It is an adjuvant resource in skin cancer surgery. 116 4 1747 1752