| dc.creator | Suppo J.-S. | |
| dc.creator | De Sant'Ana D.P. | |
| dc.creator | Dias L.C. | |
| dc.creator | De Figueiredo R.M. | |
| dc.creator | Campagne J.-M. | |
| dc.date | 2014 | |
| dc.date | 2015-06-25T18:01:03Z | |
| dc.date | 2015-11-26T15:02:49Z | |
| dc.date | 2015-06-25T18:01:03Z | |
| dc.date | 2015-11-26T15:02:49Z | |
| dc.date.accessioned | 2018-03-28T22:13:41Z | |
| dc.date.available | 2018-03-28T22:13:41Z | |
| dc.identifier | | |
| dc.identifier | Synthesis (germany). Georg Thieme Verlag, v. 46, n. 22, p. 3075 - 3084, 2014. | |
| dc.identifier | 397881 | |
| dc.identifier | 10.1055/s-0034-1379004 | |
| dc.identifier | http://www.scopus.com/inward/record.url?eid=2-s2.0-84911899566&partnerID=40&md5=05b9f185e7170dfec29d511aa6697047 | |
| dc.identifier | http://www.repositorio.unicamp.br/handle/REPOSIP/87484 | |
| dc.identifier | http://repositorio.unicamp.br/jspui/handle/REPOSIP/87484 | |
| dc.identifier | 2-s2.0-84911899566 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/1256462 | |
| dc.description | An efficient and practical procedure for the free α-carboxylic acid esterification of amino acid residues with β-(trimethylsilyl)ethoxymethyl chloride and triisopropylsilyl chloride is described. The reaction takes place under mild conditions and the expected protected amino acids are obtained in good to excellent yields. Our method provides a useful alternative for the C-terminal carboxylic acid protection of amino acids and peptides. Moreover, the removal of such protection was also achieved under mild conditions, without affecting either the other protecting groups at the α-amino moiety and side chains or the optical integrity at the α-position of the amino acid residues. Examples of their use in peptide synthesis are also illustrated. | |
| dc.description | 46 | |
| dc.description | 22 | |
| dc.description | 3075 | |
| dc.description | 3084 | |
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| dc.description | See also ref. 12For one example of chemoselective OBn ether deprotection, see ref. 13Coste, J., Le-Nguyen, D., Castro, B., (1990) Tetrahedron Lett., 31, p. 205 | |
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| dc.language | en | |
| dc.publisher | Georg Thieme Verlag | |
| dc.relation | Synthesis (Germany) | |
| dc.rights | aberto | |
| dc.source | Scopus | |
| dc.title | Efficient And Practical Procedure For The Esterification Of The Free α-carboxylic Acid Of Amino Acid Residues With β-(trimethylsilyl)ethoxymethyl Chloride And Triisopropylsilyl Chloride | |
| dc.type | Artículos de revistas | |
