Contamination by metallic mercury in urban industrial environment is one of the most important human biology aggressions that challenges health-disease relation in the collective dimension of the work world; it occurs by inhalation, ingestion or dermic contact. Because of low lipidic solubility, poisoning leads to renal insufficiency and even anuria. Clinically are presented symptoms as ataxia, tremors, hearing loss, visual field constriction, dysarthria, distal sensory loss, emotional and cognitive instability. In this paper, it is tried to explore possible relations between mercury intoxication and physical activity. As consequence, it is expected that this approach may stimulate other pioneer initiatives direct to this population group on the development of aspects as intensity, duration and frequency of specifically oriented kinesthetic programmes, aiming physiologic, neuromotor and psychosocial effects. © Copyright Moreira Jr. Editora. 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