Capítulos de libros
Rna Biomarkers In Schizophrenia
Registro en:
9780387792507
Biomarkers For Psychiatric Disorders. Springer Us, v. , n. , p. 97 - 127, 2009.
10.1007/978-0-387-79251-4_5
2-s2.0-84855455688
Autor
Martins-De-Souza D.
Dias-Neto E.
Institución
Resumen
The deciphering of the human genome and the advances in transcriptome interrogation approaches and transformed RNA biomarkers make important promises for the understanding and management of psychiatric diseases. In this chapter we describe the techniques more widely used for gene expression analysis and present the main findings in the search for RNA biomarkers in schizophrenia such as the recurrent observation of alterations in genes that encode proteins involved in pathways related to myelinization, synapses, and energy metabolism. We also discuss the main findings resultant from peripheral blood cell studies and present new techniques and new sources of RNA biomarkers for the future of research in schizophrenia. © Springer Science + Business Media, LLC 2008.
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