Artículos de revistas
Genetic Causes For Iron Deficiency [causas Genéticas De Deficiência De Ferro]
Registro en:
Revista Brasileira De Hematologia E Hemoterapia. , v. 32, n. SUPPL. 2, p. 99 - 104, 2010.
15168484
10.1590/S1516-84842010005000067
2-s2.0-78649619086
Autor
Saad S.T.O.
Institución
Resumen
The genetic causes of iron deficiency, real or functional, occur due to defects in many proteins involved in the absorption and metabolism of iron. In this chapter we briefly describe the genetic causes of iron deficiency in the synthesis of hemoglobin, resulting in hypochromic or microcytic anemia. These alterations are rare with few descriptions in the literature. In some cases, functional iron is not available for erythroblasts to synthesis hemoglobin, or erythroblasts may be incapable of capturing iron from the circulation although iron is accumulated in tissues and mitochondrias. 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