In this study, the best conditions to obtain Zinc Oxide (ZnO) nanofibers were studied for further development of a composite with a biopolymer for application in scaffolds. Although the electrospinning of ZnO nanofiber is already known, there are still new aspects to be explored to optimize itsproduction. In this work were prepared six different solutions of poly(vinyl alcohol) - PVA with two different molecular weight, containing ZnO precursor, i.e. Zinc Acetate, using water or a mix of water and alcohol as solvents, and tested to understand how solution characteristics influence the final morphology of the ZnO nanofibres. This paper shows promising results for production ceramic nanofibers by electrospinning since parameters as viscosity, molecular weight, concentration, conductivity and surface tension are well controlled. 820824Ramaseshan, R., Sundarrajan, S., Jose, R., Ramakrishna, S., Nanostructured ceramics by electrospinning (2007) J. Appl. Phys., 102, p. 102. , DecOhyama, M., Kouzuka, H., Yoko, T., Sol-gel preparation of ZnO films with extremely preferred orientation along (002) plane from zinc acetate solution (1997) Thin Solid Films, 306, pp. 78-85. , AugTakamura, N., Tagushi, K., Gunji, T., Abe, Y., Preparation of silicon oxycarbide ceramic films by pyrolysis of polyvinylsilsesquioxanes (1999) J. Sol-gel Scl. Technol., 16, p. 227. , NovLi, D., Xia, Y., Electrospinning of polymeric and ceramic nanofibers as uniaxially aligned arrays (2003) Nano Lett., 3, p. 555. , JulyGensheimer, M., Becker, M., Brandis-Heep, A., Wendorff, J.H., Thauer, R.K., Greiner, A., Novel biohybrid materials by electrospinning: Nanofibers of poly(ethylene oxide) and living bacteria (2007) Adv. Mater., 19, pp. 2480-2482. , SepKlingshirn, C., ZnO: From basics towards applications (2007) Chem. Phys. Chem., 8, pp. 782-803. , SepDing, B., Wang, M., Yu, J., Sun, G., Gas sensors based on electrospun nanofibers (2009) Sensors, 9, p. 1609. , MarchMoorer, W.R., Genet, J.M., Antibacterial activity of gutta-percha cones attributed to the zinc oxide component (1982) Oral Surg., Oral Med., Oral Pathol., 53, pp. 508-517. , MayWei, S., Zhou, M., Du, W., Improved acetone sensing properties of ZnO hollow nanofibers by single capillary electrospinning (2011) Sens. Actuators, B, 160, pp. 753-759. , DecLee, S., Multifunctionality of layered fabric systems based on electrospun polyurethane / zinc oxide nanocomposite fibers (2009) J. Appl. Polym. Sci., 114, pp. 3652-3658. , DecÖzgur, U., Alivov, Y., Liu, C., Teke, A., Reshchikov, M.A., Dogan, S., Avrutin, V., Morkoc, H., A comprehensive review of ZnO materials and devices (2005) J. Appl. Phys., 98, pp. 0413010-41301103. , AugOnozuka, K., Ding, B., Tsuge, Y., Naka, T., Yamazaki, M., Sugi, S., Ohno, S., Shiratori, S., Electrospinning processed nanofibrous TiO2 membranes for photovoltaic applications (2006) Nanotechnol., 17, p. 1026. , JanYaakob, Z., Khadem, D.J., Shahgaldi, S., Daud, W.R.W., Tasirin, S.M., The role of al and mg in the hydrogen storage of electrospun ZnO nanofibers (2002) Int. J. Hydrogen Energy, 37, pp. 8388-8394. , MayFujihara, S., Sasaki, C., Kimura, T., Effect of li and mg doping on microstructure and properties of sol-gel ZnO thin films (2001) Journal of European Ceramic Society, 21, pp. 2109-2112. , OutLi, D., Xia, Y., Electrospinning of nanofibers, reinventing the wheel? (2004) Adv. Mat., 16, pp. 1151-1170. , JulyKroski, A., Yim, K., Shivkumar, S., Effect of molecular weight on fibrous PVA produced by electrospinning (2004) Mat. Lett., 58, pp. 493-497. , JanNista, S.V.G., (2012) Desenvolvimento e Caracterização de Nanofibras de Acetato de Celulose para Liberação Controlada de Fármacos, , Masters dissertation, DEMBIO, Universidade Estadual de Campinas (UNICAMP), São PauloRamakrishna, S., Fujihara, K., Teo, W., Lim, T., Ma, Z., (2005) An Introduction to Electrospinning and Nanofibers, p. 349. , World Scientific Publishing Co. Pte. Ltd., SingaporeBetellheim, F.A., Brown, W.H., Campebell, M.K., Farrell, S.O., (2012) Introdução à Química Geral, , 9. ed. São Paulo: Cengage LearningGlordano, T.H., Drummond, S.E., The potentiometric determination of stability constants for zinc acetate complexes in aqueous solutions to 295°C (1991) Geochimica et Cosmochimica Acta, 55, pp. 2401-2415. , SepLeão, T.P., Martins, M.A., Santos, S.B., Carneiro, A.C.O., Determination of water content in ethanol by eletrical conductivity technique (2010) Global Science Technology, 3 (2), pp. 19-29. , AugJunior, W.J.P.S., Debacher, N.A., (2006) Determinação de Propriedades Superficiais Da Argila Montmorilonita Em Suspensão Aquosa de PVA Com Diferentes Graus de Hidrolise, , Universidade Federal de Santa Catarina, UFSC, Santa Catarina, SepAranha, I.B., Lucas, E.F., Poli (Álcool Vinílico) Modificado com Cadeias Hidrocarbônicas: Avaliação do Balanço Hidrófilo/Lipófilo (2001) Polímeros: Ciência e Tecnologia, 4, pp. 174-181. , NovShaw, D.J., (1975) Introduction to Colloid and Surface Chemistry, , E. BlücherFridrikh, S.V., Yu, J.H., Brenner, M.P., Rutledge, G.C., Controlling the fiber diameter during electrospinning (2003) Physical Review Letters, 40, pp. 1445021-1445024. , AprilJun, Z., Hou, H., Schaper, A., Wendorff, J.H., Greiner, A., Poly-L-lactide nanofibers by electrospinning - Influence of solution viscosity and electrical conductivity on fiber diameter and fiber morphology (2003) E-polymers, 9. , MarchUppatham, C.M., Nithitanakul, M., Supaphol, P., (2004) Ultrafine Electrospun Polyamide-6 Fibers: Effect of Solution Conditions on Morphology and Average Fiber Diameter, Macromolecular Chemistry and Physics, 205, pp. 2327-2338. , NovNishio, Y., Manley, R.S., Cellulose-poly(vinyl alcohol) blends prepared from solutions in N,N-dimethylacetamide-lithium chloride (1988) Macromol., 21, pp. 1270-1277. , MayYang, X., Shao, C., Guan, H., Li, X., Gong, J., Preparation and characterization of ZnO nanofibers by using electrospun PVA/zinc acetate composite fiber as precursor (2004) Inorg. Chem. Commun., 7, pp. 176-178. , Feb