Artículos de revistas
Specific Migration Of Antioxidant From Plastic Packages For Food [migração Específica De Antioxidante De Embalagens Plásticas Para Alimentos]
Registro en:
Polimeros. , v. 21, n. 5, p. 390 - 397, 2011.
1041428
10.1590/S0104-14282011005000064
2-s2.0-84856121164
Autor
Coltro L.
Machado M.P.
Institución
Resumen
The use of additives in plastics is essential for the processing and performance of plastic products since the additives enhance the desired characteristics of the polymers. Nevertheless, there are restrictions established by the Brazilian Agency of Sanitary Surveillance (ANVISA) for plastic packages intended to be in contact with foodstuffs which must be submitted to analyses at a proper laboratory in order to check the compliance with the requirements established. Therefore, the objective of this study was to develop a method for determining the migration of n-octadecyl 3-(3,5-ditert-butyl-4-hydroxyphenyl) propionate, antioxidant known commercially as Irganox 1076, CAS 2082-79-3, from plastic packages intended to be in contact with foodstuffs employing high performance liquid chromatography. This study also aims to ensure that commercial plastic package samples are in agreement with the requirement established by ANVISA relative to the specific migration limit for this additive. The results have shown that the methodology used for aqueous, acid and fatty simulants is satisfactory for determining the migration of Irganox 1076 since all parameters needed for the validation of the method were achieved. The LDPE and EVA filmsamples analyzed are in agreement with the specific migration limit of Irganox 1076 for all simulants evaluated. 21 5 390 397 Sarantópoulos, C., (2002) Embalagens Plásticas Flexíveis: Principais Polímeros e Avaliação de Propriedades, , ITAL/CETEA, Campinas Rabello, M., (2000) Aditivação de Polímeros, , Artliber, São Paulo Schwarzenbach, K., Gilg, B., Müller, D., Knobloch, G., Pauquet, J.-R., Rota-Graziosi, P., Schmitter, A., Zingg, J., Antioxidants (2001) Plastics Additives, Handbook, , cap.1, H. Zweifel (ed.), Hanser Publishers, Munich Coltro, L., Buratin, A.E.P., (2004) Polímeros, 14, p. 206 Wang, F.C.-Y., (2000) J. Chromatogr. A, 891, p. 325 Dispõe Sobre Regulamento Técnico Sobre Lista Positiva de Aditivos Para Materiais Plásticos Destinados à Elaboração de Embalagens e Equipamentos em Contato com Alimentos, pp. 43-51. , Agência Nacional de Vigilância Sanitária - ANVISA, Diário Oficial União, Brasília, 18 mar. 2008, Sec. I, Resolução n. 17, de 17 de Março de 2008 Nerin, C., Migración en poliolefinas (2002) Migración de Componentes y Residuos de Envases en Contacto con Alimentos, 11, pp. 205-218. , R. Catalá y R. Gavara (ed.), Valencia García, R.S., (2005) Estudio de la Migración de Distintos Componentes de los Materiales Plásticos a los Alimentos, , Tese de Doutorado, Universidade de Santiago de Compostela, Espanha Simoneau, C., Hannaert, P., (1999) Food Addit. Contam, 16, p. 197 O'Brien, A.P., Cooper, I., Tice, P.A., (1997) Food Addit. Contam., 14, p. 705 Dopico-Garcia, M.S., Lopez-Vilarino, J.M., Gonzalez-Rodriguez, M.V., (2003) J. Chromatogr. A, 1018, p. 53 Jeon, D.H., Park, G.Y., Kwak, I.S., Lee, K.H., Park, H.J., (2007) Food Sci. and Techn., 40, p. 151 Marcato, B., Guerra, S., Vianello, M., Scalia, S., (2003) Intern. J. Pharmac., 257, p. 217 Lundbäck, M., Hedenqvist, M.S., Mattozzi, A., Gedde, U.W., (2006) Polym. Degr. and Stab., 91, p. 1571 Dopico-García, M.S., López-Vilariño, J.M., González-Rodríguez, M.V., (2005) Talanta, 66, p. 1103 Sanches, S.A., Sendón, G.R., Cooper, I., Franz, R., Paseiro Losada, P., (2006) Trends in Food Sci. & Techn., 17, p. 535 Bertoldo, M., Ciardelli, F., (2004) Polymer, 45, p. 8751 Sanches, S.A., Cruz, J.M., Sendón, G.R., Franz, R., Paseiro, L.P., (2007) Meat Sci., 77, p. 238 (2009) D6953-03: Standard Test Method for Determination of Antioxidants and Erucamide Slip Additives in Polyethylene using Liquid Chromatography (LC), , American Society for Testing and Materials - ASTM (2003) Guia Para Validação de Métodos Analíticos e Bioanalíticos, , Agência Nacional De Vigilância Sanitária - ANVISA, Diário Oficial União, Brasília, 2 jul,Resolução n. 899, de 29 de Maio de 2003 (2003) Orientações Sobre Validação de Métodos de Ensaios químicos., 2, p. 25. , Instituto Nacional de Metrologia Normalização e Qualidade Industrial - INMETRO, DOQ-CGCRE-008, Rio de Janeiro, Revisão CEN/TS 13130-16: Materials and articles in contact with foodstuffs - Plastics substances subject to limitation - Part 16: Determination of caprolactam and caprolactam salt in food simulants (2005) ECS, p. 15. , European Commitee for Standardization - ECS (2010) Dispõe sobre Migração em Materiais, Embalagens e Equipamentos Plásticos Destinados a Entrar em Contato com Alimentos., pp. 75-79. , Agência Nacional de Vigilância Sanitária - ANVISA, Resolução RDC n. 51, de 26 de novembro de 2010, Diário Oficial da União, Brasília, 22 dez, Sec. I EN 13130-1:2004: Materials and articles in contact with foodstuffs - Plastics substances subject to limitation - Part 1: Guide to the test methods for the specific migration of substances from plastics to food and food simulants and the determination of substances in plastic and the selection of conditions of exposure to food simulants (2004) ECS, pp. 1-65. , European Commitee for Standardization - ECS