Artículos de revistas
Effect Of Ionizing Radiation On The Taste Function Of Patients Submitted To Head And Neck Radiotherapy [efeito Da Radiação Ionizante Sobre O Paladar Em Pacientes Submetidos A Radioterapia Para A Região Da Cabeça E Pescoço]
Registro en:
Radiologia Brasileira. , v. 44, n. 5, p. 297 - 300, 2011.
1003984
10.1590/S0100-39842011000500007
2-s2.0-80555156657
Autor
Silva A.I.V.
Galante C.
Manzi F.R.
Institución
Resumen
Objective: To evaluate the effects of ionizing radiation on the taste function in patients submitted to radiotherapy in the head and neck region. Materials and Methods: Twenty patients diagnosed with head and neck tumors and undergoing treatment in the Division of Radiotherapy at Santa Casa de Misericórdia de Belo Horizonte, MG, Brazil, were selected. For their taste function testing, four solutions were manipulated with salt (NaCl), sugar (sucrose), citric acid (for acidity), and urea (for bitterness), at three different (low, medium and high) concentrations. Weekly tests were performed during the first three weeks of radiotherapy, with random administration of the solutions (three drops each) respecting the order of their concentration levels (low, medium and high). After the application of each solution, the patient reported which flavor he/she tasted. Results: A statistically significant difference was observed in the loss of taste function as the results in the 1st and 4th weeks of treatment were compared, with salty solution at the three concentration levels, with the sweet solution at low and medium concentrations, and with the sour and bitter solutions, only at low concentration. Conclusion: Ionizing radiation alters the taste function of patients submitted to head and neck radiotherapy. © Colégio Brasileiro de Radiologia e Diagnóstico por Imagem. 44 5 297 300 Vissink, A., Burlage, F.R., Spijkervert, F.K.L., Prevention and treatment of the consequences of head and neck radiotherapy. Oral sequelae of head and neck radiotherapy (2003) Crit Rev Oral Med., 14, pp. 213-225 Sawada, N.O., Dias, A.M., Zago, M.M.F., O efeito da radioterapia sobre a qualidade de vida dos pacientes com câncer de cabeça e pescoço (2006) Rev Bras Cancerol., 52, pp. 323-329 Bonan, P.R.F., Lopes, M.A., Alves, F.A., Aspectos clínicos, biológicos, histopatológicos e tratamentos propostos para a mucosite oral induzida por radioterapia: Revisão da literatura (2005) Rev Bras Cancerol., 51, pp. 235-242 Silva, D.P., Ferraz, A.R., Durazzo, M.D., Radioterapia em cabeça e pescoço: Efeitos colaterais agudos e crônicos bucais (2004) Rev Bras Patol Oral., 3, pp. 62-69 Jham, B.C., Freire, A.R.S., Complicações bucais da radioterapia em cabeça e pescoço (2006) Rev Bras Otorrinolaringol., 72, pp. 704-708 Lima, A.A.S., Figueiredo, M.A.Z., Krapf, S.M.R., Velocidade do fluxo e pH salivar após radioterapia da região de cabeça e pescoço (2004) Rev Bras Cancerol., 50, pp. 287-293 Erkurt, E., Erkisi, M., Tunali, C., Supportive treatment in weight-losing cancer patients due to the additive adverse effects of radiation treatment and/or chemotherapy (2000) J Exp Clin Cancer Res., 19, pp. 431-439 Conger, A.D., Loss and recovery of taste acuity in patients irradiated to the oral cavity (1973) Radiat Res., 53, pp. 338-347 Tomita, Y., Osaki, T., Gustatory impairment and salivary gland pathophysiology in relation to oral cancer treatment (1990) Int J Oral Maxillofac Surg., 19, pp. 299-304 Gomez, F.E., Cassís-Nosthas, L., Morales-de-León, J.C., Detection and recognition thresholds to the 4 basic tastes in Mexican patients with primary Sjögren's syndrome (2004) Eur J Clin Nutr., 58, pp. 629-636 Scully, C., Epstein, J.B., Oral health care for the cancer patient (1996) Eur J Cancer B Oral Oncol., 32 (B), pp. 281-292 Schirdt, M., Hermund, N.U., Management of oral disease prior to radiation therapy (2002) Support Care Cancer., 10, pp. 40-43 Dobbs, J., Barrett, A., Ash, D., (1999) Practical radiotherapy planning, , London, UK: Hodder Arnold Publication Hall, E.J., (2000) Radiobiology for the radiobiologist, , Philadelphia, PA: Lippincott Williams & Wilkins Chasen, M.R., Bhargava, R., A descriptive review of the factors contributing to nutritional compromise in patients with head and neck cancer (2009) Support Care Cancer., 17, pp. 1345-1351 Kamprad, F., Ranft, D., Weber, A., Functional changes of the gustatory organ caused by local radiation exposure during radiotherapy of the head-and-neck region (2008) Strahlenther Onkol., 184, pp. 157-162