Artículos de revistas
Audiological And Genetics Studies In High-risk Infants
Registro en:
Brazilian Journal Of Otorhinolaryngology. , v. 77, n. 6, p. 784 - 790, 2011.
18088694
2-s2.0-83755184313
Autor
Colella-Santos M.F.
Francozo M.F.C.
do Couto C.M.
Lima M.C.M.P.
Tazinazzio T.G.
Castilho A.M.
Sartorato E.L.
Institución
Resumen
Hearing is one of the main ways with which one person can contact the external world; it plays a key role in their integration with society. Aim: The objective of this study was to analyze the results of the hearing, medical and genetic evaluation of high-risk infants who failed the newborn hearing screening. Materials and Methods: Clinical and experimental study. We assessed thirty-eight neonates, with ages between one and six months. The infants underwent the following procedures: medical interview; immittance testing; Brainstem Auditory Evoked Potential; Transient Evoked Otoacoustic Emission and otorhinolaryngological evaluation. DNA extraction from the oral mucosa was performed for genetic studies using the protocol method adapted from the Human Genetics Lab of the CBMEG/UNICAMP. Results: Regarding gender and presence of risk factors, significant statistically differences were not found in normal hearing infants and in those with hearing loss. Concerning gestational age, term infants were more affected by hearing loss. Hearing loss was identified in 58% of the sample, conduction hearing loss represented 31.5% (12/38) and neurossensory 28.9% of cases. There were none of the genetic mutations most commonly seen in cases with a genetic etiology. Conclusion: Hearing loss was identified in the majority of High-risk infants. 77 6 784 790 Knott, C., Universal newborn hearing screening coming soon: "hear's" why (2001) Neonatal Netw, 20 (8), pp. 25-33 Kennedy, C., McCann, D., Universal neonatal hearing screening moving from evidence to practice (2004) Arch Dis Child Fetal Neonatal Ed, 89 (5), pp. F378-F383 Northern, J.L., Hayes, D., Universal screening for infant hearing impairment: Necessary, beneficial, and justifiable (1994) Audiol Today, 6 (2), pp. 10-13 Durante, A.S., Carvalho, R.M.M., Costa, M.T.Z., Cianciarullo, M.A., Voegels, R.L., Takahashi, G.M., Programa de Triagem Auditiva Neonatal-Modelo de Implementação (2004) Arq Int Otorrinolaringol, 8 (1), pp. 40-46 Lima, G.M.L., Marba, S.T., Santos, M.F.C., Avaliação auditiva em recém-nascidos internados em Unidade de Terapia Intensiva e de Cuidados Intermediários: Triagem e acompanhamento ambulatorial (2005) Rev Cienc Med, 14 (2), pp. 147-156 Lima, G.M.L., Marba, S.T., Santos, M.F.C., Avaliação auditiva em recém-nascidos internados em UTI Neonatal (2006) J Pediatr (Rio J), 82 (2), pp. 110-114 (2010) Censo de 2000, , http://www.ibge.gov.br/censo/default.php, Instituto Brasileiro de Geografia e Estatística, Disponível em, 17 março Baroch, K.A., Universal newborn hearing screening: Finetuning process (2003) Curr Opin Otolaryngol Head Neck Surg, 11 (6), pp. 424-427 Sininger, Y., Doyle, K., Moore, J., The case for early identification of hearing loss in children (1999) Pediatr Clin North Am, 46 (1), pp. 1-14 Oliveira, P., Castro, F., Ribeiro, A., Surdez infantil (2002) Rev Bras Otor-Otorrinolaringol, 68 (3), pp. 417-423 Position Statement-2000 (2000) Am Acad Audiol, 9, pp. 1-40. , Joint Committee on Infant Hearing-JCIH Lima, G.M.L., Colella-Santos, M.F., Triagem auditiva neonatal (2009) Manual de Neonatologia Unicamp, pp. 408-411. , 2. ed, Rio de Janeiro: Revinter, In: Marba STM, Mezzacappa Filho F Durieux-Smith, A., Fitzpatrick, E., Whittingham, J., Universal newborn hearing screening: A question of evidence (2008) Int J Audiol, 47 (1), pp. 1-10 Hyde, M.L., Newborn hearing screening programs: Overview (2005) J Otolaryngol, 34 (SUPPL. 2), pp. S70-S78 Gravel, J.S., Hood, L.J., Avaliação audiológica infantil (2001) Perspectivas atuais em avaliação auditiva, pp. 301-322. , In: Musiek FE, Rintelmann WF, São Paulo: Manole; Kalatzis, V., Petit, C., The fundamental and medical impacts of recent progress in research on hereditary hearing loss (1998) Hum Mol Genet, 7 (10), pp. 1589-1597 Declau, F., Boudewyns, A., van den Ende, J., Peeters, A., Heyning, P., Analysis of 170 referred neonates etiologic and audiologic evaluations after universal neonatal hearing screening (2008) Pediatrics, 121 (6), pp. 1119-1126 Year 2007 Position statement: Principles and guidelines for early hearing detection and intervention programs (2007) Pediatrics, 120 (4), pp. 898-921. , Joint Committee on Infant Hearing Casali, R.L., Colella-Santos, M.F., Auditory Brainstem Evoked Response: Response patterns of full-term and premature infants (2010) Braz J Otorhinolaryngol, 76 (6), pp. 729-738 Linares, A.E., Carvallo, R.M.M., Medidas imitanciométricas em crianças com ausência de emissões otoacústicas (2008) Braz J Otorhinolaryngol, 74 (3), pp. 410-416 Jerger, J., Clinical experience with impedance audiometry (1970) Arch Otolaryngol, 92 (4), pp. 311-323 Carvallo, R.M.M., (2003) Fonoaudiologia: Informação para formação, pp. 344-352. , São Paulo: Guanabara-Koogan; Redondo, M.C., Lopes Filho, O., Testes básicos da avaliação auditiva (2005) Tratado de Fonoaudiologia, pp. 89-110. , In: Lopes Filho O, 2ed. Ribeirão Preto: Tecmedd; Silman, S., Silvermam, C.A., Basic Audiologic testing (1997) Auditory diagnosis: Principles and applications, pp. 44-52. , In: Silman S, Silverman CA, San Diego: Singular Publishing Group; del Castillo, F.J., Rodríguez-Ballesteros, M., Alvarez, A., Hutchin, T., Leonardi, E., de Oliveira, C.A., A novel deletion involving the connexin 30 gene del (GJB6-D13S1854) found in trans with mutations in the GJB2 gene (connexin 26) in subjects with DFNB1 nonsyndromic hearing impairment (2005) J Med Genet, 42 (7), pp. 588-594 Northern, J.L., Downs, M.P., (2005) Audição na Infância, , 5 aed. Rio de Janeiro: Guanabara Koogan; Saúde auditiva neonatal e triagem auditiva neonatal universal-TANU, , http://www.audiologiabrasil.org.br/pdf/COMUSA_final_17_maio2009, Comitê Multidisciplinar em saúde Auditiva-COMUSA Cone-Wasson, B., Vohr, B.R., Sininger, Y., Widen, J.E., Folsom, R.C., Gorga, M.P., Identification of Neonatal Hearing Impairment: Infants with Hearing loss (2000) Ear Hear, 21 (5), pp. 488-507 Boone, R.T., Bower, C.M., Martin, P.F., Failed newborn hearing screens as presentation for otitis media with effusion in the newborn population (2005) Int J Pediatr Otorhinolaryngol, 69 (3), pp. 393-397 Saes, S.O., Goldenberg, T.B.L., Montovani, J.C., Secreção na orelha mé-média em lactentes-ocorrência, recorrência e aspectos relacionados (2005) J Pediatr (Rio J), 81 (2), pp. 133-138 Almeida, C.I.R., Almeida, R.R., Orelha média aguda (2004) Tratado de Otorrinolaringologia, , In: Lopes Filho O, Campos CAH, São Paulo: Roca; Harlor, A.D.B., Bower, C., Committee on Practice and Ambulatory Medicine and the Section on Otolaryngology Head and Neck Surgery (2009) Pediatrics, 124, pp. 1252-1263 Pereira, P.K.S., Azevedo, M.F., Testa, J.R., Conductive impairment in newborn who failed the newborn hearing screening (2010) Braz J Otorhinolaryngol, 76 (6), pp. 347-354 Weckx, L.L.M., Tratamento preventivo das otites média (2006) Tratamento em Otologia, , In: Lavinsky L, Rio de Janeiro: Revinter; Doyle, K.J., Kong, Y.Y., Strobel, K., Dallaire, P., Ray, R.M., Neonatal middle ear effusion predict chronic otitis media with effusion (2004) Otol Neurotol, 25 (3), pp. 318-322 Thomé, D.C., Sanchez, T.G., Bento, R.F., Síndrome de Down e o otorrinolaringologista: Características gerais e aspectos otológicos (parte I) (1999) Arq Int Otorrinolaringol, 3 (30), pp. 93-98 Strome, M., Down's Syndrome: A modern otorhinolaryngologic perspective (1981) Laryngoscope, 91 (10), pp. 1581-1594 Sininger, Y., Hood, L., Starr, A., Berlin, C., Pinton, T., Hearing loss due to auditory neuropathy (1995) Audiol Today, 7, pp. 10-13 Rapin, I., Gravel, J., Auditory neuropathy: Physiologic and pathologic evidence calls for more diagnostic specificity (2003) Int J Pediatr Otorhinolaryngol, 67 (7), pp. 707-728 Sanyelbhaa Talaat, H., Kabel, A.H., Samy, H., Elbadry, M., Prevalence of auditory neuropathy (AN) among infants and young children with severe to profound hearing loss (2009) Int J Pediatr Otorhinolaryngol, 73 (7), pp. 937-939 Foerst, A., Beutner, D., Lang-Roth, R., Huttenbrink, K.B., von Wedel, H., Walger, M., Prevalence of auditory neuropathy/dyssynchrony in a population of children with profound hearing loss (2006) Int J Pediatr Otorhinolaryngol, 70 (8), pp. 1415-1422 Sartorato, E.L., Gottardi, E., Oliveira, C.A., Magna, L.A., Annichino-Bizzachi, J.M., Seixas, C.A., Determination of carrier frequency of the 35delG mutation in Brazilian neonates (2000) Clin Genet, 58 (4), pp. 339-340 Tekin, M., Arnos, K.S., Pandya, A., Advances in hereditary deafness (2001) Lancet, 358 (9287), pp. 1082-1090