Artículos de revistas
Scintigraphic Study Of Gastric Emptying And Intragastric Distribution Of A Solid Meal: Gender Differences [estudo Do Esvaziamento Gástrico E Da Distribuição Intragástrica De Uma Dieta Sólida Através Da Cintilografia: Diferenças Entre Os Sexos]
Registro en:
Arquivos De Gastroenterologia. , v. 37, n. 2, p. 102 - 106, 2000.
42803
2-s2.0-0034168918
Autor
Lorena S.L.S.
Tinois E.
Hirata E.S.
Cunha M.L.
Brunetto S.Q.
Camargo E.E.
Mesquita M.A.
Institución
Resumen
Gender-related differences in gastric emptying are still controversial. The aims of this study were: to confirm the sex-related difference in gastric emptying of a solid meal and to investigate its association with different patterns of meal distribution between the proximal and distal gastric compartments. Eighteen healthy volunteers (nine males, mean age 35 ± 9 years; nine females, mean age: 41 ± 11 years) were studied in the morning, after ingestion of the solid test-meal (an omelette labeled with 185MBq of 99mTc-sulfur colloid). Simultaneous anterior and posterior images of the stomach were acquired immediately after ingestion of the meal and every 10 minutes for 120 minutes. Time versus activity curves were obtained for the whole, proximal and distal stomach. Gastric T1/2 was longer in women (96.1 ± 17.2 min) than in men (79.9 ± 17.8 min; P = 0.02). The analysis of the meal distribution inside the stomach showed no differences between males and females in proximal gastric emptying, but the meal retention in the distal compartment was significantly increased among women (P = 0.04). In conclusion, gastric emptying of a solid meal is slower in pre-menopausal women than in age-matched men, probably due to an increased retention of the meal in the distal compartment. This should be taken into consideration to avoid misleading diagnosis of gastroparesis for female patients. 37 2 102 106 Bennink, R., Peeters, M., Van Den Maegdenbergh, V., Geypens, B., Rutgeerts, P., De Roo, M., Mortelmans, L., Comparison of total and compartmental gastric emptying and antral motility between healthy men and women (1998) Eur J Nucl Med, 25, pp. 1293-1299 Gill, R.C., Murphy, P.D., Hooper, H.R., Effect of menstrual cycle on gastric emptying (1987) Digestion, 36, pp. 168-174 Gryback, P., Naslund, E., Hellstrom, P.M., Jacobsson, H., Backman, L., Gastric emptying of solids in humans: Improved evaluation by Kaplan-Meyer plots, with special reference to obesity and gender (1996) Eur J Nucl Med, 23, pp. 1562-1567 Horowitz, M., Maddern, G.J., Chatterton, B.E., Collins, P.J., Harding, P.E., Shearman, D.J.C., Changes in gastric emptying rates with age (1984) Clin Sci, 67, pp. 213-218 Horowitz, M., Maddern, G.J., Chatterton, B.E., The normal menstrual cycle has no effect on gastric emptying (1985) Br J Obstet Gynecol, 92, pp. 743-746 Horowitz, M., Dent, J., Fraser, R., Sun, W., Hebbard, G., Role and integration of mechanisms controlling gastric emptying (1994) Dig Dis Sci, 39 (SUPPL.), pp. 7S-13S Hutson, W.R., Roehrkasse, R.L., Wald, A., Influence of gender and menopause on gastric emptying and motility (1989) Gastroenterology, 96, pp. 11-17 Knight, L.C., Parkman, H.P., Brown, K.L., Miller, M.A., Trate, D.C., Maurer, A.H., Fisher, R.S., Delayed gastric emptying and decreased antral contractility in normal premenopausal women compared with men (1997) Am J Gastroenterol, 92, pp. 968-975 Kumar, D., In vitro inhibitory effect of progesterone on extrauterine human smooth muscle (1962) Am J Obstet Gynecol, 84, pp. 1300-1304 Madsen, J.L., Effects of gender, age and body mass index on gastrointestinal transit times (1992) Dig Dis Sci, 37, pp. 1548-1553 McCallum, R.W., Gull, B.B., Lange, R., Planley, M., Glass, E.E., Greenfield, D.G., Definition of a gastric emptying abnormality in patients with anorexia nervosa (1985) Dig Dis Sci, 30, pp. 713-722 Read, N.W., Houghton, L.A., Physiology of gastric emptying and pathophysiology of gastroparesis (1989) Gastroenterol Clin North Am, 18, pp. 359-373 Shay, S., Eggli, D., McDonald, C., Johnson, L., Gastric emptying of solid food in patients with gastroesophageal reflux (1987) Gastroenterology, 92, pp. 459-465 J-Lc, U., Charkes, N.D., Recent advances in gastric emptying scintigraphy (1995) Sem Nucl Med, 25, pp. 318-325 Wald, A., Van Thiel, D.H., Hoechstetter, L., Gastrointestinal transit: The effect of the menstrual cycle (1981) Gastroenterology, 80, pp. 1497-1500