Actas de congresos
Real-time Monitoring Of Binding Assays On Microfluidic Devices With Contactless Conductivity Detection
Registro en:
12th International Conference On Miniaturized Systems For Chemistry And Life Sciences - The Proceedings Of Microtas 2008 Conference. Chemical And Biological Microsystems Society, v. , n. , p. 742 - 744, 2008.
2-s2.0-84902449416
Autor
Coltro W.K.T.
Da Silva J.A.F.
Carrilho E.
Institución
Resumen
This work describes the development of a dual capacitively coupled contactless conductivity detection (C4D) system and its application to monitor binding assays on microfluidic devices. Microfluidic devices were fabricated in poly(dimethylsiloxane) (PDMS) and sealed against a glass plate containing patterned electrodes. Before the sealing step, the electrodes were insulated from the contact with the microchannel by a thin layer of silicon oxide. The avidin-biotin complex was used as model system to demonstrate the analytical feasibility of the proposed system. © 2008 CBMS.
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