Artículos de revistas
Effect Of Gentamycin On Insulin Release And45ca Net Uptake By Isolated Islets
Registro en:
Experientia. Birkhäuser-verlag, v. 38, n. 11, p. 1320 - 1321, 1982.
144754
10.1007/BF01954926
2-s2.0-0020352047
Autor
Delattre E.
Santos M.L.
Boschero A.C.
Institución
Resumen
In isolated islets, gentamycin reduced both the45Ca net uptake and insulin release induced by glucose, but failed to inhibit the insulin secretion provoked by the combination of Ba2+ and theophylline. This indicates that the inhibitory effect of gentamycin is due to a reduction of Ca2+ entry into B-cells instead of to a harmful effect upon the integrity of the effector system, responsible for the extrusion of the insulin containing granules. © 1982 Birkhäuser Verlag. 38 11 1320 1321