Artículos de revistas
Subsensitivity To β-adrenoceptor Agonists In Right Atria Isolated From Footshock-stressed Rats
Registro en:
General Pharmacology. , v. 18, n. 5, p. 473 - 477, 1987.
3063623
10.1016/0306-3623(87)90065-6
2-s2.0-0023268733
Autor
Bassani R.A.
De Moraes S.
Institución
Resumen
1. The effects of three daily sessions of inescapable footshock on the sensitivity of rat isolated right atria to the chronotropic effect of norepinephrine, tyramine and soterenol were studied. 2. Inescapable footshock induces subsensitivity to norepinephrine and tyramine. The maximum response to the partial agonist soterenol was reduced. 3. In vitro denervation and addition of cocaine prevented the demonstration of inescapable footshock-induced subsentivity to norepinephrine. 4. It is concluded that repeated inescapable footshock stress reduces the number of atrial β1-adrenoceptors and increases the efficiency of the neuronal reputake process. © 1987. 18 5 473 477 Conseil General de l'Aube',Conseil National de la Recherche Scientifique (CNRS),et al,Grand Troyes,Proto Manufacturing,Region Champagne-Ardenne Aprigliano, Hermsmeyer, In vitro denervation of the portal vein and caudal artery of the rat (1976) J. Pharmac. exp. Ther., 198, pp. 568-577 Besse, Furchgott, Dissociation constants and relative efficacies of agonists acting on alpha-adrenergic receptors in rabbit aorta (1976) J. Pharmac. exp. Ther., 197, pp. 66-78 Bönisch, Fuchs, Graefe, Sodium-dependence of the saturability of carrier-mediated noradrenaline efflux from noradrenergic neurones in the rat vas deferens (1986) Naunyn-Schmiedeberg's Archives of Pharmacology, 332, pp. 131-134 Bückner, Torphy, Costa, Studies on β-adrenoceptors mediating changes in mechanical events and adenosine 3′,5′-monophosphate levels. Rat atria (1978) European Journal of Pharmacology, 47, pp. 259-271 Callia, De Moraes, Heterogeneity of beta adrenoceptors in right atria isolated from cold-exposed rats (1984) J. Pharmac. exp. Ther., 230, pp. 450-454 Chang, Tran, Snyder, Neurotransmitter receptor localization: brain lesion-induced alteration in benzodiazepine, GABA, beta-adrenergic and histamine H1-receptor binding (1980) Brain Research, 190, pp. 95-110 Harden, Agonist-induced desensitization of β-adrenergic receptor-linked adenylate cyclase (1983) Pharmac. Rev., 35, pp. 5-32 Harri, Melender, Tirri, Changed chronotropic sensitivity to sympathomimetic amines in isolated atri from rats following cold acclimation (1974) Experientia, 30, pp. 1041-1043 Hoffman, Fleshler, A relay sequencing device for scrambling grid shock1 (1967) Journal of the Experimental Analysis of Behavior, 5, pp. 329-330 Kenakin, Beek, Relative efficacy of prenalterol and pirbuterol: measurement of agonist affinity by alteration of receptor number (1984) J. Pharmac. exp. Ther., 299, pp. 340-345 Kendall, Duman, Slopes, Enna, Influence of adrenocorticotropic hormone and yohimbine on antidepressant-induced declines in rat brain neurotransmitter receptor binding and function (1982) J. Pharmac. exp. Ther., 222, pp. 566-571 Kvetnanaky, Mikulaj, Adrenal and Urinary Catecholamines in Rats During Adaptation to Repeated Immobilization Stress (1970) Endocrinology, 87, pp. 738-743 Snedecor, Cochran, (1967) Statistical Methods, , Iowa State University Press, Ames Stone, Effect of stress on norepinephrine-stimulated cyclic AMP formation in brain slices (1978) Pharmacology Biochemistry and Behavior, 8, pp. 583-591 Stone, Reduction by stress of norepinephrine-stimulated accumulation of cyclic AMP in rat cerebral cortex (1979) Journal of Neurochemistry, 32, pp. 1335-1337 Stone, Subsensitivity to norepineprhine as a link between adaptation to stress and antidepressant therapy: an hypothesis (1979) Res. Commun. Psychol. Psychiat. Behav., 4, pp. 241-255 Stone, Adaptation to stress and brain noradrenergic receptors (1983) Neuroscience & Biobehavioral Reviews, 7, pp. 503-509 Stone, McCarty, Adaptation to stress: Tyrosine hydroxylase activity and catecholamine release (1983) Neuroscience & Biobehavioral Reviews, 7, pp. 29-34 Stone, Platt, Brain Adrenergic receptors and resistance to stress (1982) Brain Research, 237, pp. 405-514 Stone, Slucky, Platt, Trullas, Reduction of the cyclic adenosine 3′-5′ monophosphate response to catecholamines in rat brain slices after repeated restraint stress (1985) J. Pharmac. exp. Ther., 233, pp. 382-388 Strader, Pickel, Joh, Strohsacker, Shore, Lefkowitz, Caron, Antibodies to the beta-adrenergic receptor: attenuation of catecholamine-sensitive adenylate cyclase and demonstration of postsynaptic receptor localization in brain. (1983) Proceedings of the National Academy of Sciences, 80, pp. 1840-1844 Torda, Yamaguchi, Hirata, Kopin, Axelrod, Mepacrine treatment prevents immobilization-induced desensitization of beta-adrenergic receptors in rat hypothalamus and brain stem (1981) Brain Research, 205, pp. 441-444 U'Prichard, Kvetnanský, Central and peripheral adrenergic receptor in acute and repeated immobilization stress (1980) Catecholamines and Stress: Recent Advances, pp. 232-299. , E. Usden, R. Kvetnanský, I.J. Kopin, Elsevier North/Holland, New York Weiss, Glazer, Pohrecky, Bailey, Schneider, Coping behaviour and stress-induced behavioral depression: studies of the role of brain catecholamines (1977) The Psychobiology of Depressive Disorders: Implications for the Effects of Stress, , R. Depul, Academic Press, New York Wolfe, Harden, Sporn, Molinoff, Presynaptic modulation of beta adrenergic receptors in rat cerebral cortex after treatment with antidepressants (1978) J. Pharmac. exp. Ther., 207, pp. 446-457