Artículos de revistas
Role Of 17 β-estradiol On Type Iv Collagen Fibers Volumetric Density In The Basement Membrane Of Bladder Wall
Registro en:
International Urogynecology Journal And Pelvic Floor Dysfunction. , v. 18, n. 10, p. 1185 - 1190, 2007.
9373462
10.1007/s00192-006-0294-4
2-s2.0-35648973749
Autor
de Fraga R.
Dambros M.
Miyaoka R.
Riccetto C.L.Z.
Palma P.C.R.
Institución
Resumen
The authors quantified the type IV collagen fibers volumetric density in the basement membrane of bladder wall of ovariectomized rats with and without estradiol replacement. This study was conducted on 40 Wistar rats (3 months old) randomly divided in 4 groups: group 1, remained intact (control); group 2, submitted to bilateral oophorectomy and daily replacement 4 weeks later of 17 β-estradiol for 12 weeks; group 3, sham operated and daily replacement 4 weeks later of sesame oil for 12 weeks; and group 4, submitted to bilateral oophorectomy and killed after 12 weeks. It was used in immunohistochemistry evaluation using type IV collagen polyclonal antibody to stain the fibers on paraffin rat bladder sections. The M-42 stereological grid system was used to analyze the fibers. Ovariectomy had an increase effect on the volumetric density of the type IV collagen fibers in the basement membrane of rat bladder wall. Estradiol replacement in castrated animals demonstrated a significative difference in the stereological parameters when compared to the castrated group without hormonal replacement. Surgical castration performed on rats induced an increasing volumetric density of type IV collagen fibers in the basement membrane of rats bladder wall and the estradiol treatment had a significant effect in keeping a low volumetric density of type IV collagen fibers in the basement membrane of rats bladder wall. © International Urogynecology Journal 2007. 18 10 1185 1190 Miodrag, A., Castleden, C.M., Guayanés, T.R., Sex hormones and the female urinary tract (1988) Drugs, 36, pp. 491-504 Fleischmann, N., Christ, G., Sclafani, T., Melman, A., The effect of ovariectomy and long-term estrogen replacement on bladder structure and function in the rat (2002) J Urol, 168, pp. 1265-1268 Schlussel, R.N., Droller, M.J., Liu, B.C.S., Type IV procollagen mRNA regulation: Evidence for extracellular matrix/ cytoskeleton/nuclear matrix interactions in human urothelium (1991) J Urol, 146, pp. 428-432 Parsons, C.L., Lilly, J., Stein, P., Epithelial dysfunction in nonbacterial cystitis (Interstitial cystitis) (1991) J Urol, 145, pp. 732-735 Hurst, R.E., Rhodes, S.W., Adamson, P.B., Functional and structural characteristics of the glycosaminoglycans of the bladder luminal surface (1987) J Urol, 38, pp. 433-437 Conn, I.G., Basement membrane in urothelial carcinoma (1987) Brit J Urol, 60, pp. 536-542 Abrahanson, D.R., Recent studies on the structure and pathology of basement membranes (1986) J Pathol, 149, pp. 257-278 Martinez-Hernandez, A., Amenta, P.S., The basement membrane in pathology (1983) Lab Invest, 48, pp. 656-677 Mathieu, O., Cruz-Orive, L.M., Hoppeler, H., Weibel, E.R., Measuring error and sampling variation in stereology: Comparison of the efficiency of various methods for planar image analysis (1981) J Microsc, 121, pp. 75-88 Cotrim, A.E.I., Pardi, P.C., Sakumoto, S., Simões, M.J., Morfometria e estereologia: Algumas considerações gerais (1990) Acta Cir Bras, 5, pp. 28-30 Cruz-Orive, L.M., Weibel, E.R., Recent stereological methods for cell biology: A brief survey (1990) Am J Physiol, 258, pp. L148-L156 Rocha, M.A., Sartori, M.G., Girao, M.J., De Jesus Simoes, M., Baracat, E.C., Histomorphometric study of the inferior urinary tract of adult female rats during the interval between castration and hormonal replacement (2003) Clin Exp Obstet Gynecol, 30 (2-3), pp. 111-116. , Rodrigues of Lima Hextall, A., Oestrogens and lower urinary tract function (2000) Maturitas, 36, pp. 83-92 Klutke, J.J., Bergman, A., Hormonal influence on the urinary tract (1985) Urol Clin North Am, 22, pp. 629-639 Wehba, S., Ferreira, J.S., Grinbaum, M.L., Yoneda, V.R., Fernandes, C.E., Azevedo, L.H., Efeitos clínicos e virológicos da administraçe̊o de estrogênio percutâneo em mulheres menopausadas (1997) Reprod Clim, 12, pp. 194-196 Hashimoto, T., Ishigooka, M., Zerman, D.H., Effects of estrogen and progesterone on urinary bladder in female rabbit: Evaluation by quantitative morphometric analysis (1990) Urology, 53, pp. 642-646 Dambros, M., Palma, P.C.R., Lacerda, M., Miyaoka, R., Netto Jr., N.R., The effect of ovariectomy and estradiol replacement on collagen and elastic fibers in the bladder of rats (2003) Int Urogynecol J, 14, pp. 108-112 Murakumo, M., Ushiki, T., Abe, K., Matsumura, K., Shinno, Y., Koyanagi, T., Three-dimensional arrangement of collagen and elastin fibers in the human urinary bladder: A scanning electron microscopic study (1995) J Urol, 154, pp. 251-256 Kiyofuji, M.A., Iyama, K., Kitaoka, M., Sado, I.Y., Ninomiya, Y., Ueda, S., Quantitative analysis of type IV collagen alpha chains in the basement membrane of human urogenital epithelium (2002) Histochem J, 34 (10), pp. 479-486 Rodriguez, L.V., Wang, B., Shortliffe, L.M., Structural changes in the bladder walls of pregnant and hormone treated rats: Correlation with bladder dynamics (2004) BJU Int, 94 (9), pp. 1366-1372