Artículos de revistas
Hb Indianapolis [β112 (g14) Cys→arg] As The Probable Cause Of Moderate Hemolytic Anemia And Renal Damage In A Brazilian Patient
Registro en:
American Journal Of Hematology. , v. 82, n. 7, p. 672 - 675, 2007.
3618609
10.1002/ajh.20860
2-s2.0-34347351133
Autor
Fattori A.
Kimura E.M.
Albuquerque D.M.
Oliveira D.M.
Costa F.F.
Sonati M.D.F.
Institución
Resumen
Hemoglobin (Hb) Indianapolis [β112 (G14) Cys→Arg] is a rare and slightly unstable β-globin variant. All carriers described to date were clinically normal with only mild reticulocytosis. We report here a case of a Brazilian patient in whom hemolytic anemia and acute renal failure were probably caused by the presence of this variant. © 2007 Wiley-Liss, Inc. 82 7 672 675 Dacie, J.V., Lewis, S.M., (1995) Practical Haematology, , 8th ed. London: Churchill Livingstone; Miranda, S.R.P., Fonseca, S.F., Figueiredo, M.S., Hb Köln [α 2β 2 98 (FG) Val→Met] identified by DNA analysis in a Brazilian family (1997) Braz J Genet, 20, pp. 745-748 Bunn, H.F., Forget, B.G., (1986) Hemoglobin: Molecular Genetics and Clinical Aspects, , Philadelphia:W.B. Saunders Company; Williamson, D., The unstable haemoglobins (1993) Blood Rev, 7, pp. 146-163 Winterbourn, C.C., Oxidative denaturation in congenital hemolytic anemias: The unstable hemoglobins (1990) Semin Hematol, 27, pp. 41-50 Lutz, H.U., Flepp, R., Stringaro-Wipf, G., Naturally occurring auto antibodies to exoplasmic and cryptic regions of band 3 protein, the major integral membrane protein of human red blood cells (1984) J Immunol, 133, pp. 2610-2618 Adams III, J.G., Boxer, L.A., Baehner, R.L., Hemoglobin Indianapolis (β 112[G14]arginine). An unstable β-chain variant producing the phenotype of severe β-thalassemia (1979) J Clin Invest, 63, pp. 931-938 Baiget, M., Gomez Pereira, C., Jue, D.L., A case of hemoglobin Indianapolis [β 112(G14) Cys-Arg] in an individual from Cordoba, Spain (1986) Hemoglobin, 10, pp. 483-494 De Biasi, R., Spiteri, D., Caldora, M., Identification by fast atom bombardment mass spectrometry of Hb Indianapolis [β 112(G14)Cys-Arg] in a family from Naples, Italy (1988) Hemoglobin, 12, pp. 323-336 Coleman, M.B., Steinberg, M.H., Adams III, J.G., Hemoglobin Terre Haute arginine β 106. A posthumous correction to the original structure of hemoglobin Indianapolis (1991) J Biol Chem, 266, pp. 5798-5800 HbVar Database, , http://globin.cse.psu.edu, accessed July 2006 Winterbourn, C.C., Williamson, D., Vissers, M.C., Carrell, R.W., Unstable haemoglobin haemolytic crises: Contributions of pyrexia and neutrophil oxidants (1981) Br J Haematol, 49, pp. 111-116