Artículos de revistas
Fibrosarcoma Originating In The Mandible
Registro en:
Medicina Oral, Patologia Oral Y Cirugia Bucal. , v. 11, n. 3, p. 191 - 194, 2006.
16984447
2-s2.0-33745074073
Autor
Soares A.B.
Lins L.H.S.
Macedo A.P.
Pereira Neto J.S.
Vargas P.A.
Institución
Resumen
Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this article we describe a case of primary fibrosarcoma in the mandible in a 16-year-old girl. Microscopically the tumor showed an intense proliferation of spindle-shaped cells, varying little in size and shape and arranged in parallel bands, partly crossing each other, the mitotic activity was increased and there was nuclear pleomorphism. Immunohistochemically the cells only showed immunoreactivity for vimentin and negativity for S-100 protein, CD 68, cytokeratin cocktail, HMB-45, CD34, pan actin HHF 35, desmin, smooth muscle actin and epithelial membrane antigen (EMA). Based on clinical, radiological, histological and immunohistochemical findings the final diagnosis was high-grade intra-osseous fibrosarcoma. The treatment choice was radical surgery with mandibular reconstruction. After one year and nine months of the treatment the patient displayed multiple metastases. Radiation therapy and chemotherapy were used as adjuvant treatment. Unfortunately, the girl died two years after the initial diagnosis. © Medicina Oral S. L. C.I.F. B 96689336. 11 3 191 194 Lo Muzio, L., Mignogna, M.D., Pannone, G., Staibano, S., Testa, N.F., A rare case of fibrosarcoma of the jaws in a 4-year-old male (1998) Oral Oncol, 34, pp. 383-386 Richardson, J.F., Fine, M.A., Goldman, H.M., Fibrosarcoma of the mandible: A clinicopathologic controversy: Report of a case (1972) J Oral Surg, 30, pp. 664-668 Mark, R.J., Sercarz, J.A., Tran, L., Selch, M., Calcaterra, T.C., Fibrosarcoma of the Head and Neck. The UCLA experience (1991) Arch Otolaryngol Head Neck Surg, 117, pp. 396-401 McKenna, W.G., Barnes, M.M., Kinsella, T.J., Rosenberg, S.A., Lack, E.E., Glatstein, E., Combined modality treatment of adult soft tissue sarcomas of the head and neck (1987) Int J Radiat Oncol Biol Phys, 13, pp. 1127-1133 Van Blarcom, C.W., Masson, J.K., Dahlin, D.C., Fibrosarcoma of the mandible. A clinicopathologic study (1971) Oral Surg Oral Med Oral Pathol, 32, pp. 428-439 Sadoff, R.S., Rubin, M.M., Fibrosarcoma of the mandible: A case report (1990) J Am Dent Assoc, 121, pp. 247-248 Handlers, J.P., Abrams, A.M., Melrose, R.J., Milder, J., Fibrosarcoma of the mandible presenting as a periodontal problem (1985) J Oral Pathol, 14, pp. 351-356 Pereira, C.M., Jorge Junior, J., Di Hipólito, O., Kowalski, L.P., Lopes, M.A., Primary intraosseous fibrosarcoma of jaw (2005) Int J Oral Maxillofac Surg, 34, pp. 579-581 Antonescu, C.R., Erlandson, R.A., Huvos, A.G., Primary fibrosarcoma and malignant fibrous histiocytoma of bone - A comparitive ultrastructural study: Ecidence of a spectrum of fibroblastic differentiation (2000) Ultrastruct Pathol, 24, pp. 83-91 Mosqueda-Taylor, A., Meneses-García, A., Ruíz-Godoyrivera Lm Suárez-Roa, M.I., Luna-Ortiz, K., Malignant odontogenic tumors. A retrospective and collaborative study of seven cases (2003) Med Oral, 8, pp. 110-121 Huguet, P., Castellvi, J., Avila, M., Alejo, M., Autonell, F., Basas, C., Ameloblastic fibrosarcoma: Report of a case. Immunohistochemical study and review of the literature (2001) Med Oral, 6, pp. 173-179 Yamaguchi, S., Nagasawa, H., Suzuki, T., Fujii, E., Iwaki, H., Takagi, M., Sarcomas of the oral and maxillofacial region: A review of 32 cases in 25 years (2004) Clin Oral Invest, 8, pp. 52-55 Lukinmaa, P.L., Hietanen, J., Swan, H., Ylipaavalniemi, P., Perkki, K., Maxillary fibrosarcoma with extracellular immuno-characterization (1988) Br J Oral Maxillofac Surg, 26, pp. 36-44