Artículos de revistas
Nutritional Supplementation Assessment With Whey Proteins And Tgf-β In Patients With Crohn's Disease [evaluación Del Efecto De La Suplementación Con Proteínas Del Suero De La Leche Y El Tgf-β, En Pacientes Con Síndrome De Crohn]
Registro en:
Nutricion Hospitalaria. , v. 27, n. 4, p. 1286 - 1292, 2012.
2121611
10.3305/nh.2012.27.4.5795
2-s2.0-84864311492
Autor
Davanco T.
Oya V.
Saddy Rodrigues Coy C.
Franco Leal R.
de Setsuko Ayrizono M.L.
Sgarbieri V.C.
dos Santos Vilela M.M.
Lomazi E.A.
Institución
Resumen
Crohn's disease (CD) is a chronic inflammatory disorder that primarily affects the intestines, resulting in breakage of the intestinal barrier, pathological inflammation and nutritional disorders that encompass from trace elements deficiency to severe malnutrition. Nutritional interventions either alone or associated to drug therapy may be effective to achieve and maintain inflammation remission. Objective: To evaluate usual food intake as quantitative and qualitatively, in CD patients; and describe the effect of a supplement containing whey proteins and TGF- on their body composition. Patients and methods: Dietary intake was assessed considering 42 consecutive patients, followed in a tertiary center, and by using the 3-day food recall and food intake frequency questionnaire. Body composition was assessed previously and 8 weeks after supplementation with a diet containing whey proteins and TGF-β (N = 22). Results and discussion: Considering carbohydrates and lipids, most patients had adequate dietary intake according recommendations. Protein, saturated fat, B12 vitamin and zinc intakes were higher than the recommended values. The dietary fiber, A, D, C and E vitamins, calcium, iron, folate, potassium and sodium intakes did not reach the recommended requirements in most patients. Patients supplemented with the whey protein and TGF-β dietary presented a positive increment in their lean body mass, when compared to non-supplemented group. Conclusion: CD patients require nutritional orientation. Whey protein intake resulted in significant differences, such as improvement in Lean Body Mass and reduction in Fat percentage. 27 4 1286 1292 Coeffier, M., Marion-Letellier, R., Déchelotte, P., Potential for Amino Acids Supplementation During Inflammatory Bowel Diseases (2010) Inflammatory Bowel Disease, 16 (3), pp. 518-524 Griffiths, A.M., Enteral nutrition in the management of Crohn's disease (2004) JPEN J Parenter Enteral Nutr, 29 (SUPPL. 4), pp. S108-S112 Bounous, G., Pal, K., Gold, P., The Immunoenhancing Property of Dietary Whey Protein Concentrate (1988) Clinical and Investigative Medicine, 11 (4), pp. 271-278 Pacheco, M.T.B., Bighetti, E., Antônio, M., Carvalho, J.E., Rosaneli, C.F., Sgarbieri, V.C., Efeito de um hidrolisado de proteínas de soro de leite e de seus peptídeos na proteção de lesões ulcerativas da mucosa gástrica de ratos (2006) Revista De Nutrição, Campinas, 19 (1), pp. 47-55 Tassi, E.M.M., Amaya-Farfán, J., Azevedo, R.A., Hydrolyzed α-lac-talbumin as a source of protein to the exercising rat (1998) Nutrition Research. Tarrytown, 18, pp. 875-881 McIntosh, G.H., Rogester, G.O., Whey proteins as functional food ingredient (1998) International Dairy Journal, Barking, 8, pp. 425-434 Brink, W., (1996) The Life Extension Protein: That Fights Disease and Extends Lifespan, 1, pp. 21-28. , Life Extension Report, Life Extension Foundation, Scottsdale (1989) Subcommittee On the Tenth Edition of the RDAs Food and Nutrition Board Commission On Life Sciences National Research Council National Academy Pres, , Recommended dietary allowances, 10th Edition. Washington, D.C Tabela Brasileira De Composição De Alimentos - Unicamp (TACO), , http://wwwunicamp.br/nepa/taco/ WHO/FAO Diet, nutrition and prevention of chronic diseases. Report of Joint. WHO/FAO Expert Consultation. Geneva: WHO, 2003 (Technical Report Series, 916)(2001) Dietary Reference Intakes: Applications In Dietary Assessment, , http://www.nap.edu, Institute of Medicine, Washington DC: The National Academy Press, cited 2007 July 14 Long, C.L., Schaffel, N., Geiger, J.W., Metabolic response to injury and illness: Estimation of energy and protein needs from indirect calorimetry and nitrogen balance (1979) JPEN, 3, pp. 452-456 Durnin, J.V.G.A., Rahaman, M.M., The assessment of the amount of fat in the human body from measurements of skin fold thickness (1967) British Journal of Nutrition, pp. 681-689 (2004) Estratégia Global Para a Alimentação Saudável, Atividade Física E Saúde: 57° Assembléia Mundial De Saúde: WHO 57.17.8a Sessão Plenária De 22 De Maio De 2004 (versão Em Português, Tradução Não Oficial), , Organização Mundial da Saúde (OMS), S.I Cuppari, L., (2006) Nutrição Clínica No Adulto. 2° Ed, , São Paulo: Manole Rodrigues, S.R., Passoni, C.M.S., Paganotto, M., (2008) Aspectos Nutricio-nais Na Doença De Crohn, 1, pp. 1-8. , Cadernos da Escola de Saúde Nutri-ção Chicharro, S.L., La fibra como tratamiento de enfermida-des intestinales (2007) El Farmacéutico Hospitales, 187, pp. 7-13 Rodrigues-Cabezas, M.E., Galvez, J., Lorente, M.D., Dietary fiber down regulates colonic tumor necrosis factor alpha and nitric oxide production I trinitrobenzenesulfonuc acid-induced colitis rats (2002) J Nutr, 132, pp. 3263-3271 Mattos, L.L., Martins, S.I., Consumo de fibras alimentares em popu-lação adulta (2000) Revista De Saúde Pública, 34 (1), pp. 50-55 Consumo Alimentar: Antropometria - Dados Preliminares, , Fundação IBGE, Rio de Janeiro 1975. Pt 1. Região I, Pt 3. Região II. (Estudo Nacional da Despesa Familiar) Ballesteros, P., Vidal Casariego, A., Calleja Fernandéz, A., López Gómez, J.J., Urioste Fondo, A., Cano Rodríguez, I., Impact of nutritional treatment in the evolution of inflammatory bowel disease (2010) Nutr Hosp, 25 (2), pp. 181-192 Slater, B., Marchioni, D.L., Fisberg, R.M., Estimando a prevalên-cia da ingestão inadequada de nutrientes (2004) Revista De Saúde Pública, 38 (4), pp. 599-605 Bounous, G., Whey protein concentrate (WPC) and glutathione modulation in cancer treatment (2000) Anticancer Res, 20 (6 C), pp. 4785-4792 Lands, L.C., Grey, V.L., Smountas, A.A., Effect of supplementation with a cysteine donor on muscular performance (1999) J Appl Physiol, 87, pp. 1381-1385 Inelmen, E.M., Sergi, G., Coin, A., Miotto, F., Peruzza, S., Enzi, G., Can obesity be a risk factor in elderly people? (2003) Obesity Reviews, 4 (3), pp. 147-155 Xavier Pi-Sunyer, F., The Obesity Epidemic: Pathophysiology and Consequences of Obesity (2002) Obesity Research, 10, pp. 97S-104S Cribb Paul, B.H., (2006) Proteí-nas De Soro E Composição Corporal, , Sc. HMS, B. Chem. Sci. (Hons) CSCS, U.S. Dairy Expot Council Hack, V., Schmid, D., Breitkreutz, R., Cystine levels, cystine flux, and protein catabolism in cancer cachexia, HIV/SIV infection and senescence (1997) FASEB J, 11, pp. 84-92 Ha, E., Zemel, M.B., Functional properties of whey, whey components, and essential amino acids: Mechanisms underlying health benefits for active people (2003) J Nutr Biochem, 14 (5), pp. 251-258 Bouthegourd, J.J., Roseau, S.M., Makarios-Lahham, L., A pre-exercise lactalbuminenriched whey protein meal preserves lipid oxidation and decreases adiposity in rats (2002) Am J Physiol Endocrinol Metab, 283, pp. E565-E572 Calbet, J.A.L., Maclean, D.A., Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans (2002) J Nutr, 132 (8), pp. 2174-2182