Actas de congresos
Public Sphere And The Sustainability Of The Bioinformatics Promise
Registro en:
Genetics And Molecular Research. Fundacao De Pesquisas Cientificas De Ribeirao Preto, v. 3, n. 4, p. 575 - 581, 2004.
16765680
2-s2.0-14644444598
Autor
Leite M.
Institución
Resumen
The literature about genomics and bioinformatics achievements in high-impact journals such as Nature and Science has raised disproportionate expectations amongst the general public about fast and revolutionary drugs and breakthroughs in biomedicine. However, the yield obtained by database mining activities has been modest, as reported in the February 2001 issues of these journals featuring the completion of human genome draft sequences by the Human Genome Project Consortium and the company Celera. I have compared changes in rethoric employed by molecular biologists in 2001 and in April 2003, when the final sequence was announced. The comparison suggests that researchers are concerned about the sustainability of society's investment in this field, though not explicitly. © FUNPEC-RP. 3 4 575 581 Baltimore, D., Our genome unveiled (2001) Nature, 409, pp. 814-816 Birney, E., Bateman, A., Clamp, M.E., Hubbard, T.J., Mining the draft human genome (2001) Nature, 409, pp. 827-828 Bork, P., Copley, R., Filling in the gaps (2001) Nature, 409, pp. 818-820 Butler, D., Are you ready for the revolution? (2001) Nature, 409, pp. 758-760 Collins, F., Green, E.D., Guttmacher, A.E., Guyer, M.S., A vision for the future of genomics research. A blueprint for the genomic era (2003) Nature, 422, pp. 835-847 Collins, F., Morgan, M., Patrinos, A., The Human Genome Project: Lessons from large-scale biology (2003) Science, 300, pp. 286-296 Frazier, M.E., Johnson, G.M., Thomassen, D.G., Oliver, C.E., Patrinos, A., Realizing the potential of the genome revolution (2003) Science, 300, pp. 290-293. , The Genomes to Life Program Galas, D.J., Making sense of the sequence (2001) Science, 291, pp. 1257-1260 Lander, E.S., Linton, L.M., Birren, B., Initial sequencing and analysis of the human genome (2001) Nature, 409, pp. 860-921 Malakoff, D., Service, R.F., Genomania meets the bottom line (2001) Science, 291, pp. 1193-1203 Pollard, T.D., Genomics, the cytoskeleton and motility (2001) Nature, 409, pp. 842-843 Tupler, R., Perini, G., Green, M., Expressing the human genome (2001) Nature, 409, pp. 832-833 Venter, J., Remington, K., Heidelberg, J.F., Environmental genome shotgun sequencing of the Sargasso Sea (2004) Science, 304, pp. 66-74