The temporal medial sclerosis (TMS) is characterized by hippocampal sclerosis in temporal and by distinghished grades of injury near to other neurological structures such as: amygdaloid nucleus, parahippocampal girus and entorhinal region. The study analyzed 40 patients with TMS and 40 people from the control cluster. All the cases were appreciated by one method for measurement of insula's cortex (E-Film) and another method to calculate the insula's volume (Neuroline). There is no variation statistical between the insula's volume and insula's measurement for the two clusters. This paper didn't show the insula's morphological variation when these two groups were compared.A esclerose medial temporal (EMT) é caracterizada pela esclerose hipocampal e diferentes graus de acometimento das estruturas vizinhas como amígdala, giro parahipocampal e córtex entorrinal. O estudo avaliou 40 indivíduos com EMT e 40 do grupo controle. Os casos foram avaliados por um método para as medidas da ínsula (E-Film) e outro método para o cálculo do volume (Neuroline). Não houve diferença estatística de alteração de volume e das medidas do lobo da ínsula nos pacientes portadores de EMT. O estudo não demonstrou alteração morfológica da ínsula quando comparado os dois grupos.639644