Osseous dysplasias are idiopathic processes located in theperiapical region of the maxillary-mandibular complex. They are characterized by the substitution of normal osseous tissue for fi brous tissue and metaplastic osseous tissue. Florid osseous dysplasia (FOD) describes a set of radio-lucid and radio opaque inter-radicular and periapical lesions, bilaterally found in the mandible and sometimes in the upper jaw. The present project presented a FOD case diagnosed by means of histological, radiological and clinical findings; there was presence of infection and painful symptoms. A 62 year old female patient treated at the Oral-Maxillofacial Surgery Unit of the General Hospital «Dr. Domingo Luciani», Caracas, Venezuela sought medical care. The patient reported onset of the condition two weeks before consultation, she experienced intense pain in the right mandibular posterior region with presence of intraoral fistula and purulent discharge. X-ray examination revealed multiple radio-opaque lesions involving all four quadrants. Excision biopsy was undertaken, histopathological study indicated presence of florid osseous dysplasia. The patient was assessed during an 11 month asymptomatic post-operative period.