The aim of this study was to assess the  magnitude of horizontal, vertical and transverse variations in Centric Relation (CR) in patients afflicted with temporomandibular dysfunction(TMD) as well as otologic symptoms (OS) when compared with asymptomatic patients . This comparison was achieved using an MG2 articulator. Patients were subject to study at the Stomatology-Orthodontics Division of the General Hospital “Dr Manuel Gea Gonzalez” (GHMGG)- The study was conducted in the time span included from 2005 to 2006, with patient ages ranking from 20 to 60 years.This study was carried out on 27 patients afflicted with TMD and OS and 15 patients who did not suffer from the aforementioned conditions.Results of the present study showed that  TMD and OS patients presented horizontal, vertical and transverse discrepancy  in relation with maximum intercuspation  (MI) and significant central relation (CR). Anterior-posterior variations were found in 15 of the 27 studied cases. Vertical variations were less significant and were found only in ten of the studied cases.