Tesis
Efecto Hipoglucemiante del Extracto de las Hojas de Frutipan (Artocarpus altilis), en Ratas (Rattus novergicus) con Hiperglicemia Inducida.
Fecha
2012-02-17Registro en:
León Encalada, Jacqueline Victoria. (2012). Efecto Hipoglucemiante del Extracto de las Hojas de Frutipan (Artocarpus altilis), en Ratas (Rattus novergicus) con Hiperglicemia Inducida. Escuela Superior Politécnica de Chimborazo. Riobamba.
Autor
León Encalada, Jacqueline Victoria
Resumen
To prove the hipoglucemiante effect of the leaves or Frutipan (Artocarpus altilis) in rats
(Rattus novergicus), with induced hyperglycacmia through scientific analytical method
determining the levels of glycacmia for that purpose blood samples were taken through a
glucometer to the 30 minutes, 6-18-24-36 hours. 18 rats were used, they were divided in 6
groups called: TI (doses to the 100% extract of Frutipan), B (white), C+ (positive control),
C- (negative control). A Bioterio was developed in the Biochemical and Pharmacy in the
ESPOCH, the diabetic animals were gotten through the administration of an overload of
glucose in doses of 35%. The groups: Tl, T2, T3, reccived like extract of the Frutipan leaves
treatment, respectively with a concentration of 100%, 50%, 25%. The negative control group
received distilated water more glucose to the 35%, the white group and positive control
vchicle only. For the analysis of data gathered, the ANOVA TEST was used (varianzas
analysis) and T=student. Aer having applied the treatment extract of the Frutipan extract, it
was established the reduction of glycacmia in blood gotten from the following average
values: White 75.5 mg/dL; positive control 70.5 mg/dl; negative control 89 mg/dl; group TI
66.6 mg/dl; group T2 69mg/dl; group T3 76.6 mg/dl. The glucose reduces in 100% of the
basal glucose in doses of high and medium concentration (100%). This contributes to spread
the data gathered in the rescarch theme to the population because it is an important
contribution for diabetic people to bear their situation.