https://repositorioslatinoamericanos.uchile.cl/handle/2250/8848601 Sat, 04 Apr 2026 23:08:02 GMT 2026-04-04T23:08:02Z https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899179 Modulation of antibiotic resistance by the essential oil of Ocimum gratissimum L. in association with light-emitting diodes (LED) lights Centro Universitário Dr. Leão Sampaio (Unileão); Universidade Regional do Cariri (URCA); This study aimed to evaluate the antibacterial and antibiotic-enhancing effects of the essential oil obtained from Ocimum gratissimum L. (OEOg) alone or in association with light-emitting diodes (LED) lights. The essential oil was obtained by hydrodistillation and its chemical composition analysed by gas chromatography coupled to mass spectrometry. The antibacterial and antibiotic-enhancing activities against multiresistant strains of Staphylococcus aureus and Escherichia coli were evaluated by the gaseous contact method. The analysis of the photoinductive effect on the antibacterial activity of the OEOg and antibiotics was assessed through exposure to different LED lights (red, blue and yellow). The phytochemical analysis identified five compounds, including eugenol, as the major constituent. The OEOg caused a significant inhibition of the halo, indicating a direct antibacterial effect. Exposure to the LED lights significantly enhanced the activity of the OEOg against E. coli. On the other hand, the action of the essential oil against S. aureus was enhanced by exposure to both blue and yellow lights. The effects of LED light exposure on the activity of conventional antibiotics varied significantly according to the drug and the bacterial strain. However, most combinations of LED lights and the OEOg presented synergistic effects against resistant bacterial strains, indicating enhanced antibacterial activity. Thus, these in vitro findings suggest that both OEOg and LED lights have promising antibacterial effects. Nevertheless, further research is required to evaluate in vivo the potential of these therapies for the treatment of infectious skin diseases. https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899179 https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899180 II Encontro da Rede Sudeste de Repositórios Institucionais: Sudeste RIAA: 22 de julho A transmissão do evento foi realizada pela VideoSaúde Distribuidora, por meio de seu canal no YouTube: https://www.youtube.com/videosaudedistribuidoradafiocruz; Cerimonial: Renata Rezende (Icict/Ascom) / Apresentação dos palestrantes: Catarina Barreto Malheiro Pereira (Icict/Seção de Informação).; O evento foi promovido e realizado pela RIAA/Sudeste, organizado pela Fundação Oswaldo Cruz (Fiocruz), por meio do Instituto de Comunicação e Informação Científica e Tecnologia em Saúde (Icict/Fiocruz). Nos dois dias do Encontro, houveram palestras técnicas sobre temas relacionados aos repositórios institucionais e sua importância para a salvaguarda dos documentos produzidos pelas Instituições. No dia 22, foi a vez de Maria de Fátima Correa (VPEIC/Fiocruz), Marisa Raquel (Universidad Nacional de La Plata – Argentina), Mariangela Spotti Lopes Fujita (Unesp) e Angelica Conceição Dias Miranda (FURG), que falaram sobre o papel dos repositórios, a situação do Sistema Nacional de Repositórios Digitais da Argentina, a política de indexação para repositórios e o uso dos repositórios digitais no ensino, pesquisa e extensão. https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899180 https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899178 Catálogo sistemático dos pólens das plantas arbóreas do Brasil meridional (Parte complementar: Coniferales) RESUMO EM ALEMÃO:In Ergaenzung des 1. Teils des Katalogs der Baumpollen Sued-brasiliens werden die drei einzigen hier vorkommenden Gymnospermaearten beschrieben: Araucaria angustifolia, Podocarpus sellowii und P. lamberti. Die erste besitzt runde, mit zwei Ausbuchtungen versehene Pollen und eine komplex gebaute Exine. Beide Podocarpusarten aehneln einander sehr. Bezueglich ihrer Groesse koennen sie nicht voneinander geschieden werden. Die beste Art der Unterscheidung besteht in der Oberflaechenstruktur der Pollenkoerper: P. sellowii hat eine feine, engmaschige, anaehernd netzartige oberflaeche (entsprechend dem "reticulate-ornate" = Typ), waehrend P. lamberti grobe Erhebungen (entsprechend dem "ornate" = typ) vorweist. https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899178 https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899175 Breast-cancer extracellular vesicles induce platelet activation and aggregation by tissue factor-independent and -dependent mechanisms Cancer-associated thrombosis is one of the major causes of worse prognosis among tumor-bearing patients. Extracellular vesicles derived from cancer cells, which can be divided mainly into microvesicles and exosomes, can participate in several tumor progression phenomena. Tumor-derived microvesicles positive for tissue factor (TF) have been associated with thrombotic risk in certain cancer types. Cancer cell-derived exosomes, however, have not. In this study we evaluated the capacity of extracellular vesicles (EVs, containing both microvesicles and exosomes) derived from breast-cancer cell lines in promoting platelet activation, aggregation and plasma coagulation, in experiments that access both TF-dependent and -independent activities.; 2030-01-01 https://repositorioslatinoamericanos.uchile.cl/handle/2250/8899175