https://repositorioslatinoamericanos.uchile.cl/handle/2250/6444568 2026-04-28T20:24:25Z https://repositorioslatinoamericanos.uchile.cl/handle/2250/9276176 C-Abl tyrosine kinase inhibitory compound embodiments and methods of making and using the same. Disclosed herein are embodiments of a compound that inhibits c-Abl tyrosine kinase (also referred to herein as “c-Abl”). The compound embodiments described herein are novel c-Abl inhibitors that can bind to c-Abl at an allosteric site and inhibit its activity in various pathways. The compound embodiments also are capable of crossing the blood brain barrier and therefore are useful in inhibiting c-Abl activity as it affects pathways and/or proteins in the brain. The compound embodiments described herein are effective therapeutic agents for treating diseases involving c-Abl, such as cancers, motor neuron diseases, and neurodegenerative diseases. Also disclosed herein are embodiments of methods for making and using the c-Abl inhibitory compound embodiments 2023-01-01T00:00:00Z https://repositorioslatinoamericanos.uchile.cl/handle/2250/9276178 Linear and Nonlinear Structure-Soil-Structure Interaction During Earthquakes 2021-01-01T00:00:00Z https://repositorioslatinoamericanos.uchile.cl/handle/2250/9276177 Historia reciente de la derecha chilena. Antipartidismo e independientes 2001-01-01T00:00:00Z https://repositorioslatinoamericanos.uchile.cl/handle/2250/9276179 Sujeto y nacion en la configuracion de la literatura autobiografica chilena The objective of this thesis is to investigate the concepts of" subject" and" nation" in autobigraphical works in Chile, and how these concepts are demonstrated. The group of works examined here cover a period that extends from the mid-nineteenth to the seventies in the twentieth century. 1996-01-01T00:00:00Z