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Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry
(Elsevier Science Inc, 2018-06)
Background: Evidence for the comparative teratogenic risk of antiepileptic drugs is insufficient, particularly in relation to the dosage used. Therefore, we aimed to compare the occurrence of major congenital malformations ...
Características Dismórficas E Desenvolvimento Neurocomportamental De Filhos De Mães Com Epilepsia Generalizada Genética Após A Exposição Intraútero Aos Fármacos Antiepilépticos: Um Estudo Observacional
(Universidade Federal de São Paulo (UNIFESP), 2017-07-31)
Objective: To analyze pregnancies of mothers with genetic generalized epilepsy (M-GGE) regarding seizure control, treatment, and outcome; cognitive impairment, dysmorphic features (DF), and major congenital malformations ...
Uso del valproato de sodio intravenoso en el tratamiento del estado epiléptico en niños: revisión sistemática de ensayos clínicos controlados aleatorizados
(2014)
El estado epiléptico es una condición clínica que amenaza la vida de forma aguda y es causa de importantes secuelas neurológicas a largo plazo. Además de las benzodiazepinas de corta acción, solo la Fenitoina y el ...
Treating alcohol use disorder in U.S. veterans: The role of traumatic brain injury
(American Neuropsychiatric Association, 2019-10)
Objective: The authors examined the efficacy of valproate to reduce relapse to heavy drinking among veterans with alcohol use disorder (AUD) and neuropsychiatric comorbidities and whether antecedent traumatic brain injury ...
How does lithium compare with mood stabilizers for people with acute mania?
(Wiley, 2019-12)
For adults with acute mania, the effects of lithium compared with different mood stabilizers were mixed, and although differences were noted, few reached statistical significance. The comparative adverse effect pattern ...
A inibição da recaptação de dopamina pelo GBR12909 como um possível modelo animal de mania: aspectos comportamentais, farmacológicos e neuroimunológicos
(Universidade Federal de Minas GeraisUFMG, 2015-12-01)
Bipolar disorder (BD) is a psychiatric disorder featured by the occurrence of mania and depression episodes. The pharmacological treatment consists in mood stabilizers, including lithium and valproate. In addition, ...