Now showing items 11-20 of 81
Hereditary hemoglobinopathies in a population from southeast Brazil
(Marcel Dekker IncNew York, 1996)
p53 Mutant Human Glioma Cells Are Sensitive to UV-C-Induced Apoptosis Due to Impaired Cyclobutane Pyrimidine Dimer Removal
(AMER ASSOC CANCER RESEARCH, 2009)
The p53 protein is a key regulator of cell responses to DNA damage, and it has been shown that It sensitizes glioma cells to the alkylating agent temozolomide by up-regulating the extrinsic apoptotic pathway, whereas it ...
Physiological, morphological, and mannanase production studies on Aspergillus niger uam-gs1 mutants
(Pontificia Universidad Católica de Valparaíso, 2006)
Functional characterization of the putative Aspergillus nidulans DNA damage binding protein homologue DdbA
Nucleotide excision repair (NER) eliminates helix-distorting DNA base lesions. Seven XP-deficient genetic complementation groups (XPA to XPG) have already been identified in mammals, and their corresponding genes have been ...
Divergent functions of the Arabidopsis mitochondrial SCO proteins: HCC1 is essential for COX activity while HCC2 is involved in the UV-B stress response
The two related putative cytochrome c oxidase (COX) assembly factors HCC1 and HCC2 from Arabidopsis thaliana are Homologs of the yeast Copper Chaperones Sco1p and Sco2p. The hcc1 null mutation was previously shown ...
Genetic interactions of the Ashergillus nidulans atmA(ATM) homolog with different components of the DNA damage response pathway
Ataxia telangiectasia mutated (ATM) is a phosphatidyl-3-kinase-related protein kinase that functions as a central regulator of the DNA damage response in eukaryotic cells. In humans, mutations in ATM cause the devastating ...
The interplay of UV and cutaneous papillomavirus infection in skin cancer development
(Public Library Of Science, 2017-11)
Cutaneous human papillomaviruses (HPVs) are considered as cofactors for non-melanoma skin cancer (NMSC) development, especially in association with UVB. Extensively studied transgenic mouse models failed to mimic all aspects ...
Communication: UV photoionization of cytosine catalyzed by Ag+
(American Institute of Physics, 2015-07)
The photo-induced damages of DNA in interaction with metal cations, which are found in various environments, still remain to be characterized. In this paper, we show how the complexation of a DNA base (cytosine (Cyt)) with ...