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Interactions between the NO-Citrulline Cycle and Brain-derived Neurotrophic Factor in Differentiation of Neural Stem Cells
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INCBETHESDA, 2012)
The diffusible messenger NO plays multiple roles in neuroprotection, neurodegeneration, and brain plasticity. Argininosuccinate synthase (AS) is a ubiquitous enzyme in mammals and the key enzyme of the NO-citrulline cycle, ...
Exploration of the Antiplatelet Activity Profile of Betulinic Acid on Human Platelets
(AMER CHEMICAL SOCWASHINGTON, 2012)
Betulinic acid, a natural pentacyclic triterpene acid, presents a diverse mode of biological actions including antiretroviral, antibacterial, antimalarial, and anti-inflammatory activities. The potency of betulinic acid ...
A negative screen for mutations in calstabin 1 and 2 genes in patients with dilated cardiomyopathy
(BioMed CentralLondon, 2012)
Background
Calstabins 1 and 2 bind to Ryanodine receptors regulating muscle excitation-contraction coupling. Mutations in Ryanodine receptors affecting their interaction with calstabins lead to different cardiac pathologies. ...
Physics and its interfaces with medicinal chemistry and drug design
(SpringerNew York, 2013-08)
Medicinal chemistry is a multidisciplinary subject that integrates knowledge from a variety of fields of science, including, but not limited to, chemistry, biology, and physics. The area of drug design involves the cooperative ...
Curcumin requires tumor necrosis Factor α signaling to alleviate cognitive impairment elicited by Lipopolysaccharide
(KargerBasel, 2013)
A decline in cognitive ability is a typical feature of the normal aging process, and of neurodegenerative disorders such as Alzheimer’s, Parkinson’s and Huntington’s diseases. Although their etiologies differ, all of these ...
Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts
(BMC, 2008-01-14)
Background
Cytoadherence of Plasmodium falciparum -infected red blood cells is mediated by var gene-encoded P. falciparum erythrocyte membrane protein-1 and host receptor preference depends in most cases ...
Divergent calcium signaling in RBCs from Tropidurus torquatus (Squamata – Tropiduridae) strengthen classification in lizard evolution
(2007-08-23)
Abstract
Background
We have previously reported that a Teiid lizard red blood cells (RBCs) such as Ameiva ameiva and Tupinambis merianae controls intracellular calcium levels ...
Var transcription profiling of Plasmodium falciparum 3D7: assignment of cytoadherent phenotypes to dominant transcripts
(Biomed Central, 2008)
Abstract
Background
Cytoadherence of Plasmodium falciparum -infected red blood cells is mediated by var gene-encoded P. falciparum erythrocyte membrane protein-1 and host ...
Divergent calcium signaling in RBCs from Tropidurus torquatus (Squamata – Tropiduridae) strengthen classification in lizard evolution
(2007)
Abstract
Background
We have previously reported that a Teiid lizard red blood cells (RBCs) such as Ameiva ameiva and Tupinambis ...
Divergent calcium signaling in RBCs from Tropidurus torquatus (Squamata – Tropiduridae) strengthen classification in lizard evolution
(2007-08-23)
Abstract
Background
We have previously reported that a Teiid lizard red blood cells (RBCs) such as Ameiva ameiva and Tupinambis merianae controls intracellular calcium levels ...