Now showing items 31-40 of 16638
Synergy of DNA-bending nucleoid proteins and macromolecular crowding in condensing DNA
Many prokaryotic nucleoid proteins bend DNA and form extended helical protein-DNA fibers rather than condensed structures. On the other hand, it is known that such proteins (such as bacterial HU) strongly promote DNA ...
Aromatic clusters in protein-protein and protein-drug complexes
(BioMed Central, 2020-05)
Aromatic rings are important residues for biological interactions and appear to a large extent as part of protein-drug and protein-protein interactions. They are relevant for both protein stability and molecular recognition ...
Ab initio protein folding simulations using atomic burials as informational intermediates between sequence and structure
The three-dimensional structure of proteins is determined by their linear amino acid sequences but decipherment of the underlying protein folding code has remained elusive. Recent studies have suggested that burials, as ...
Protein folding assisted by chaperones
(Bentham Science Publ LtdSharjahEmirados Árabes Unidos, 2005)
Protein Repeats from First Principles
(Nature Publishing Group, 2016-04)
Some natural proteins display recurrent structural patterns. Despite being highly similar at the tertiary structure level, repeating patterns within a single repeat protein can be extremely variable at the sequence level. ...
Use of 13Ca chemical-shifts in protein structure determination
(American Chemical Society, 2007-05)
A physics-based method aimed at determining protein structures by using NOE-derived distances together with observed and computed 13C chemical shifts is proposed. The approach makes use of 13Cα chemical shifts, computed ...
A structural appraisal of sterol carrier protein 2
(Elsevier Science, 2017-05)
Sterol Carrier Protein 2 (SCP2) has been associated with lipid binding and transfer activities. However, genomic, proteomic, and structural studies revealed that it is an ubiquitous domain of complex proteins with a variety ...
BeEP Server: using evolutionary information for quality assessment of protein structure models
(Oxford University Press, 2013-07)
The BeEP Server (http://www.embnet.qb.fcen.uba.ar/embnet/beep.php) is an online resource aimed to help in the endgame of protein structure prediction. It is able to rank submitted structural models of a protein through an ...